5-(4-Bromophenyl)-4,6-pyrimidinediol: A Vital Pharmaceutical Intermediate
Explore the synthesis, properties, and critical role of this key chemical intermediate in modern drug development.
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5-(4-Bromophenyl)-4,6-pyrimidinediol
This compound stands as a cornerstone in the production of advanced pharmaceutical agents. Its precise chemical structure and high purity make it indispensable for synthesizing complex active pharmaceutical ingredients (APIs), notably playing a critical role in the manufacturing pathway of macitentan, a significant therapeutic for pulmonary arterial hypertension. Understanding the detailed synthesis and properties of this intermediate is key for efficient pharmaceutical manufacturing.
- Discover the precise synthesis of 5-(4-bromophenyl)-4,6-pyrimidinediol, a critical step in pharmaceutical manufacturing.
- Learn about the key applications of this chemical intermediate, particularly its role in macitentan production.
- Explore the physical and chemical properties, including its appearance as a white powder and high purity levels (>=98.0%).
- Understand the importance of intermediates for drug discovery and the development of new therapeutic solutions.
Key Advantages for Pharmaceutical Synthesis
High Purity Guarantee
Achieve superior results in your pharmaceutical synthesis with our 5-(4-bromophenyl)-4,6-pyrimidinediol, guaranteed to have a purity of ≥98.0%. This high purity minimizes side reactions and ensures the efficacy of the final drug product.
Critical for Macitentan Production
As a key intermediate for macitentan, this compound supports the development of treatments for pulmonary arterial hypertension. Reliance on quality intermediates like this is crucial for reliable API production.
Versatile Chemical Intermediate
Beyond macitentan, the unique structure of 5-(4-bromophenyl)-4,6-pyrimidinediol makes it a valuable building block for various other pharmaceutical and fine chemical syntheses, driving innovation in drug discovery.
Key Applications
Macitentan Synthesis
This compound is an indispensable precursor in the multi-step synthesis of Macitentan, a vital medication for treating pulmonary arterial hypertension. Its reliable supply supports consistent drug manufacturing.
Pharmaceutical Intermediates
Serving as a high-quality intermediate, it enables the efficient production of various Active Pharmaceutical Ingredients (APIs), contributing to advancements in medicinal chemistry and patient care.
Research and Development
In R&D settings, 5-(4-bromophenyl)-4,6-pyrimidinediol is utilized for exploring novel synthetic routes and developing new chemical entities with potential therapeutic benefits.
Fine Chemical Manufacturing
Its well-defined properties and consistent quality make it a sought-after material in the broader fine chemical industry for custom synthesis projects and specialized chemical production.