Trans-N,N'-Dimethylcyclohexane-1,2-Diamine, a compound identified by CAS number 67579-81-1, is a molecule of significant interest in the field of organic chemistry and pharmaceutical development. NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide an overview of its key chemical properties and its diverse applications in synthesis.

The physical characteristics of trans-N,N'-Dimethylcyclohexane-1,2-Diamine are important for its handling and application. It typically presents as a colorless or light yellow liquid, with a density around 0.9 g/cm³. Its boiling point is approximately 186.8 °C at standard atmospheric pressure, indicating a relatively stable liquid state under typical processing conditions. The melting point of 4°C means it remains liquid at most ambient temperatures. Furthermore, its flash point of around 60.2 °C necessitates careful handling in terms of ignition sources.

Chemically, trans-N,N'-Dimethylcyclohexane-1,2-Diamine is a diamine, featuring two secondary amine groups attached to a cyclohexane ring in a trans configuration. This structural feature imparts specific reactivity. Its molecular formula is C8H18N2, with a molecular weight of 142.242. The Polar Surface Area (PSA) is 24.06000 and its LogP value is 0.35, suggesting a moderate balance between hydrophilicity and lipophilicity, which can influence its solubility and interaction in different chemical environments. These properties are crucial for its role as a versatile intermediate in various synthetic pathways.

The applications of trans-N,N'-Dimethylcyclohexane-1,2-Diamine are primarily concentrated within the pharmaceutical industry. As a key pharmaceutical intermediate, it is instrumental in the synthesis of complex drug molecules. Most notably, it is a precursor for Oxaliplatin, a crucial agent in cancer chemotherapy. Its structure allows for precise control during the formation of the platinum-carbon bonds characteristic of this drug class. Beyond Oxaliplatin, its utility extends to other areas of medicinal chemistry where chiral diamines are employed as ligands or building blocks.

Researchers and industrial chemists value trans-N,N'-dimethylcyclohexane-1,2-diamine for its ability to introduce specific structural motifs and chirality into target molecules. The consistent availability of high-purity material from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is essential for ensuring reproducible results in demanding synthetic processes. Its role in facilitating key chemical reactions underscores its importance as a foundational chemical for innovation in drug discovery and development.

In conclusion, the well-defined chemical properties and broad applicability of trans-N,N'-Dimethylcyclohexane-1,2-Diamine make it an indispensable compound in modern chemical synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying this vital intermediate to support advancements in the pharmaceutical and chemical industries worldwide.