The Chemical Synthesis and Properties of 2-Amidinopyrimidine Hydrochloride at NINGBO INNO PHARMCHEM CO.,LTD.
At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in providing high-quality chemical reagents and intermediates, and 2-Amidinopyrimidine Hydrochloride (CAS: 138588-40-6) is a prime example of our commitment to excellence. This compound, known for its utility in pharmaceutical synthesis and materials science, is produced with meticulous attention to its synthesis pathways and physicochemical properties.
The preparation of 2-Amidinopyrimidine Hydrochloride typically involves several established chemical synthesis routes. Historically, methods like the Chichibabin reaction were used, but modern industrial synthesis often focuses on more efficient and scalable processes. A common approach involves the conversion of 2-cyanopyrimidine to its amidine hydrochloride salt. This process, often optimized for high yields and purity, requires careful control of reaction conditions, including temperature, solvent, and reagent ratios. NINGBO INNO PHARMCHEM CO.,LTD. utilizes advanced synthetic methodologies to ensure the consistent production of high-purity 2-Amidinopyrimidine Hydrochloride, meeting the demanding specifications of our clients.
Understanding the physicochemical properties of 2-Amidinopyrimidine Hydrochloride is crucial for its effective application. It is typically supplied as a white to light yellow powder. Key properties include a melting point of 180-183°C (with sublimation), a molecular weight of 158.589 g/mol, and a density of 1.39 g/cm³. Its solubility profile indicates it is generally soluble in polar solvents, facilitating its use in various reaction media. These detailed specifications are essential for researchers and manufacturers to accurately incorporate the compound into their processes, whether for pharmaceutical intermediates or material science applications.
The versatility of 2-Amidinopyrimidine Hydrochloride stems from its chemical structure, featuring both a pyrimidine ring and an amidine group. This bifunctional nature allows it to participate in a wide range of chemical reactions, including cycloadditions, alkylations, and cross-coupling reactions. Such reactivity makes it an indispensable component in the synthesis of more complex molecules, including Bosentan and potential anticancer agents. The reliable availability of this compound, guaranteed by NINGBO INNO PHARMCHEM CO.,LTD., empowers innovation in these critical fields.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to advancing chemical research and industrial applications by providing dependable access to essential compounds like 2-Amidinopyrimidine Hydrochloride. Our expertise in chemical synthesis and quality assurance ensures that our clients receive products that meet the highest standards, thereby supporting their research and development endeavors.
Perspectives & Insights
Chem Catalyst Pro
“Its solubility profile indicates it is generally soluble in polar solvents, facilitating its use in various reaction media.”
Agile Thinker 7
“These detailed specifications are essential for researchers and manufacturers to accurately incorporate the compound into their processes, whether for pharmaceutical intermediates or material science applications.”
Logic Spark 24
“The versatility of 2-Amidinopyrimidine Hydrochloride stems from its chemical structure, featuring both a pyrimidine ring and an amidine group.”