2-Formyl-3,4-dihydro-2H-pyran (CAS 100-73-2) is a chemical compound that plays a pivotal role as an intermediate in a multitude of industrial processes. Its classification as a cyclic aldehyde, derived from the dimerization of acrolein, bestows upon it a unique reactivity profile that is highly sought after in organic synthesis. This article will explore its fundamental chemical properties, common synthesis routes, and essential safety protocols for its handling and use.

Chemically, 2-Formyl-3,4-dihydro-2H-pyran presents as a colorless to yellow liquid, often characterized by a pungent and disagreeable odor. Its physical properties, such as a boiling point of approximately 146°C and a flash point around 54°C, classify it as a flammable liquid, necessitating careful handling. The compound's solubility in water, albeit slight, and its density contribute to its behavior in various chemical reactions. Understanding these characteristics is fundamental for efficient chemical intermediate manufacturing.

The synthesis of 2-Formyl-3,4-dihydro-2H-pyran typically involves the dimerization of acrolein. Various methods have been developed to optimize this process, including thermal catalysis and microwave-assisted synthesis, aiming for higher yields and purity. Research into these synthesis of 2-Formyl-3,4-dihydro-2H-pyran pathways is ongoing, seeking more sustainable and cost-effective production methods. For laboratories and industries, knowing where to buy 2-Formyl-3,4-dihydro-2H-pyran of high quality is paramount.

Safety is a critical consideration when working with this compound. As indicated by its hazard symbols and risk codes, it can be irritating to the eyes and mucous membranes, and potentially harmful if inhaled or absorbed through the skin. Proper personal protective equipment, adequate ventilation, and adherence to Material Safety Data Sheet (MSDS) guidelines are essential to mitigate risks. Employers must ensure that workers are aware of the hazards associated with CAS 100-73-2 and are trained in safe handling procedures.

The utility of 2-Formyl-3,4-dihydro-2H-pyran as a building block in the synthesis of pharmaceuticals, plastics, and agrochemicals cannot be overstated. Its consistent availability and the ability to procure it at competitive prices for 2-Formyl-3,4-dihydro-2H-pyran support its widespread use. By understanding its chemistry and handling it with appropriate care, industries can continue to leverage this versatile intermediate for innovation and product development.