The development of advanced pharmaceuticals relies heavily on the precise synthesis of complex chemical compounds. (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride (CAS: 1156491-10-9) is a prime example of such a critical intermediate, playing an indispensable role in the manufacturing process of Ticagrelor, a leading medication for preventing thrombotic events in patients with acute coronary syndromes.

At its core, this compound is a stereochemically defined cyclopropane derivative featuring a difluorophenyl substituent and an amine group, stabilized as a hydrochloride salt. The significance of its exact (1R,2S) configuration cannot be overstated; it is this specific spatial arrangement of atoms that dictates its reactivity and its ability to form the correct structure in the final Ticagrelor molecule. A high assay purity, typically exceeding 98.0%, is also a critical attribute, ensuring minimal contamination and maximum efficiency in subsequent synthetic steps. The compound is commonly presented as a white to yellow powder, a characteristic indicative of its purity and manufacturing quality.

The synthesis pathway for Ticagrelor heavily incorporates this intermediate. Pharmaceutical manufacturers worldwide depend on a consistent and high-quality supply to ensure uninterrupted production. This demand has fostered a specialized niche within the fine chemical industry, where companies like NINGBO INNO PHARMCHEM CO.,LTD. have emerged as key players. By offering this intermediate, along with robust manufacturing capabilities and adherence to quality standards, such suppliers enable pharmaceutical companies to meet the global demand for Ticagrelor.

Understanding the chemical properties and handling requirements of (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride is essential for its effective use. Proper storage in cool, ventilated conditions helps maintain its chemical integrity. For businesses looking to buy this product, exploring various suppliers and comparing their offerings in terms of price, quantity, and technical support is a standard practice. The competitive landscape for pharmaceutical intermediates means that finding a reliable chemical supplier in China, such as NINGBO INNO PHARMCHEM CO.,LTD., can provide a significant advantage in cost-effectiveness and supply chain security.

The journey from a basic chemical intermediate to a life-saving drug like Ticagrelor is complex, involving meticulous chemical synthesis and stringent quality control. (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride is a testament to the advancements in organic chemistry and its application in modern medicine. Its role highlights the importance of specialized chemical manufacturers who can consistently deliver high-purity, stereochemically accurate compounds, thereby supporting the development and accessibility of essential pharmaceuticals for improving public health.

In essence, the chemical precision and availability of (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride are foundational to the production of Ticagrelor. Companies that prioritize a strong relationship with experienced manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are better positioned to navigate the complexities of API synthesis and contribute to global healthcare solutions.