4-Formylphenylboronic acid (CAS No: 87199-17-5) is a chemical compound that holds significant importance in the fine chemical and pharmaceutical industries. Its unique structure, featuring both an aldehyde group and a boronic acid moiety, makes it a versatile reagent for a wide array of synthetic transformations. Understanding its chemistry is crucial for chemical suppliers aiming to serve the pharmaceutical sector and research institutions.

The synthesis of 4-Formylphenylboronic acid typically involves the functionalization of phenylboronic acid derivatives. Common synthetic routes often employ palladium-catalyzed cross-coupling reactions or direct formylation of substituted phenylboronic acids. The ability to achieve high purity, often specified at ≥98.0%, is critical for its subsequent use in pharmaceutical applications. The physical properties, such as its appearance as a white to light yellow crystal powder, are important indicators for quality control by suppliers.

The primary drivers for the demand of 4-Formylphenylboronic acid are its applications as a key intermediate in the synthesis of important pharmaceuticals. It plays a vital role in the production of Atazanavir, a crucial drug for HIV treatment, and Rucaparib, a targeted therapy for certain cancers. These applications highlight the compound's direct contribution to improving human health and underscore the need for a stable and reliable supply chain for pharmaceutical intermediates.

For chemical suppliers, offering 4-Formylphenylboronic acid requires a deep understanding of these applications and the stringent quality requirements of the pharmaceutical industry. Beyond its pharmaceutical uses, its utility in general organic synthesis, particularly in Suzuki-Miyaura couplings, makes it a valuable product for academic research and the development of new materials. The boronic acid functional group's participation in C-C bond formation is a cornerstone of modern synthetic chemistry.

As the pharmaceutical landscape continues to evolve, with an increasing focus on complex molecule synthesis and targeted therapies, the demand for versatile and high-purity intermediates like 4-Formylphenylboronic acid is expected to remain strong. Chemical suppliers who can consistently deliver this compound with the required specifications are well-positioned to support innovation in drug discovery and development, contributing to the advancement of medical science.