The Chemistry of Coagulation: Exploring Ethyl 6-(4-Aminophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate and Apixaban
The development of effective anticoagulants has revolutionized the treatment of cardiovascular diseases and thrombotic disorders. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying the chemical building blocks essential for these life-saving medications, including compounds like Ethyl 6-(4-Aminophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate (CAS: 503615-07-4).
This molecule is intrinsically linked to Apixaban, a potent inhibitor of coagulation factor Xa. By targeting factor Xa, Apixaban effectively disrupts the coagulation cascade, preventing the formation of blood clots. This mechanism is crucial for managing conditions like atrial fibrillation and preventing devastating events such as strokes and pulmonary embolisms.
The synthesis of Apixaban is a complex multi-step process, and intermediates like Ethyl 6-(4-Aminophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate are indispensable. Its specific structure, C22H22N4O4 with a molecular weight of 406.43, provides the foundational scaffold upon which the final Apixaban molecule is constructed. The quality and purity of this intermediate directly influence the quality of the API.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to ensuring that pharmaceutical researchers and manufacturers have access to these critical chemical components. Our role goes beyond simple supply; we are partners in innovation, providing materials that enable advancements in medical treatments. Understanding the chemical properties of compounds such as CAS 503615-07-4 is vital for optimizing synthesis routes and ensuring the consistent production of high-quality pharmaceuticals.
The therapeutic benefits derived from Apixaban, such as the prevention of venous thromboembolism in orthopedic surgery and the management of thromboembolic disorders, are a direct result of sophisticated chemical synthesis and rigorous quality control. Compounds like Ethyl 6-(4-Aminophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate are the silent heroes behind these medical breakthroughs. NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to this vital sector.
Perspectives & Insights
Core Pioneer 24
“This molecule is intrinsically linked to Apixaban, a potent inhibitor of coagulation factor Xa.”
Silicon Explorer X
“By targeting factor Xa, Apixaban effectively disrupts the coagulation cascade, preventing the formation of blood clots.”
Quantum Catalyst AI
“This mechanism is crucial for managing conditions like atrial fibrillation and preventing devastating events such as strokes and pulmonary embolisms.”