The Critical Link: Isobutylboronic Acid in Bortezomib Production
In the intricate landscape of pharmaceutical chemistry, certain compounds serve as linchpins, enabling the creation of complex and life-altering medications. Isobutylboronic Acid (CAS: 84110-40-7) is one such compound, recognized for its indispensable role as a crucial intermediate in the synthesis of Bortezomib. Bortezomib, a first-in-class proteasome inhibitor, has transformed the treatment paradigms for multiple myeloma and mantle cell lymphoma, offering renewed hope to patients worldwide. The effectiveness and reliability of Bortezomib are directly influenced by the quality of its precursor materials, making the precise specifications of Isobutylboronic Acid of utmost importance.
Chemically identified as 2-methylpropylboronic acid, with the molecular formula C4H11BO2, Isobutylboronic Acid is characterized by its physical appearance as a white to off-white powder. The industry standard for its purity is typically ≥99%, supported by low levels of ash (≤0.1%) and moisture (≤0.5% loss on drying). These stringent quality controls are not merely technical details; they are fundamental to ensuring the success of the multi-step synthesis required to produce Bortezomib. For pharmaceutical manufacturers looking to buy Isobutylboronic Acid, these quality markers are critical indicators of product integrity and suitability for GMP-compliant production.
The strategic importance of Isobutylboronic Acid in the pharmaceutical supply chain cannot be overstated. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are vital players, providing a consistent and high-quality source for this essential intermediate. Their ability to reliably supply Isobutylboronic Acid ensures that the production of Bortezomib is not hindered by material shortages or quality inconsistencies. Understanding the price of Isobutylboronic Acid also reflects its value as a precision-engineered component for advanced therapeutic development. Access to this compound at a fair market price is essential for making advanced cancer treatments accessible.
To maintain the efficacy of Isobutylboronic Acid, specific storage conditions must be observed. It is recommended to store the material at 0-6°C, in a tightly sealed container, protected from moisture and direct heat or light. These precautions are crucial for preserving the compound's purity and reactivity for its intended use. When considering the purchase of Isobutylboronic Acid, it is important to partner with suppliers who provide detailed guidance on handling and storage, such as NINGBO INNO PHARMCHEM CO.,LTD., who offer packaging in 25kg cardboard drums. Such diligence in sourcing and handling is key to the successful production of life-saving pharmaceuticals.
Perspectives & Insights
Bio Analyst 88
“To maintain the efficacy of Isobutylboronic Acid, specific storage conditions must be observed.”
Nano Seeker Pro
“It is recommended to store the material at 0-6°C, in a tightly sealed container, protected from moisture and direct heat or light.”
Data Reader 7
“These precautions are crucial for preserving the compound's purity and reactivity for its intended use.”