The Critical Role of High-Purity 1-Hydroxyethylethoxypiperazine in Pharmaceutical Manufacturing
In the intricate world of pharmaceutical manufacturing, the quality of raw materials and intermediates is paramount. Among these vital components, 1-Hydroxyethylethoxypiperazine stands out as a critical intermediate, particularly for the synthesis of widely used antipsychotic medications like Quetiapine and its fumarate salt. Sourcing this compound with exceptional purity is not merely a preference but a necessity for ensuring the efficacy, safety, and consistency of the final Active Pharmaceutical Ingredient (API).
The chemical, identified by CAS number 13349-82-1, is characterized by its structure, featuring a piperazine ring linked to an ethoxyethanol chain. This specific molecular architecture makes it an ideal precursor in multi-step synthesis pathways. Manufacturers seeking to buy 1-Hydroxyethylethoxypiperazine often look for products with an assay of ≥99.5%, as indicated in detailed product specifications. This high level of purity is crucial because impurities, even in small amounts, can lead to side reactions, reduced yields, and potentially compromise the pharmacological profile of the end product. For instance, controlling N-Hydroxyethylpiperazine (HEP) and other related impurities is vital for regulatory compliance and product performance.
The synthesis of Quetiapine fumarate, a cornerstone in treating conditions such as schizophrenia and bipolar disorder, relies heavily on the quality of its intermediates. A reliable 1-Hydroxyethylethoxypiperazine supplier ensures that manufacturers can maintain efficient production cycles. The physical and chemical properties, such as its density and boiling point, are also important considerations for optimizing reaction conditions and ensuring safe handling. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are dedicated to providing this essential chemical intermediate, understanding its pivotal role in the pharmaceutical supply chain.
Furthermore, the demand for this compound extends beyond its primary application. As a versatile piperazine derivative, it can be explored in other fine chemical synthesis projects that require specific heterocyclic structures. The ability to source this chemical with guaranteed low impurity levels and consistent quality empowers pharmaceutical companies to streamline their manufacturing processes, reduce post-synthesis purification steps, and ultimately bring vital medications to market more efficiently. The commitment to quality from suppliers ensures that the journey from chemical intermediate to life-saving drug is robust and dependable.
Perspectives & Insights
Future Origin 2025
“As a versatile piperazine derivative, it can be explored in other fine chemical synthesis projects that require specific heterocyclic structures.”
Core Analyst 01
“The ability to source this chemical with guaranteed low impurity levels and consistent quality empowers pharmaceutical companies to streamline their manufacturing processes, reduce post-synthesis purification steps, and ultimately bring vital medications to market more efficiently.”
Silicon Seeker One
“The commitment to quality from suppliers ensures that the journey from chemical intermediate to life-saving drug is robust and dependable.”