The Critical Role of (R)-4-Propyldihydrofuran-2(3H)-one in Modern Pharmaceutical Manufacturing
(R)-4-Propyldihydrofuran-2(3H)-one, identified by CAS number 63095-51-2, is a compound of significant interest within the pharmaceutical industry. Its primary claim to fame lies in its indispensable role as a chiral intermediate in the synthesis of Brivaracetam, a potent antiepileptic drug. The intricate process of bringing effective medications to market relies heavily on the quality and availability of such intermediates, and understanding their properties and production is key.
The compound itself is described as a yellow oily liquid, exhibiting moderate solubility in common organic solvents like chloroform, methanol, and ethanol. This physical characteristic dictates specific handling and storage conditions, typically requiring refrigeration between 2-8°C to maintain its integrity. The precise stereochemistry of (R)-4-Propyldihydrofuran-2(3H)-one is not merely an academic detail; it is fundamental to the pharmacological activity of the final drug, Brivaracetam. This makes its enantiomeric purity a critical parameter in its manufacturing process.
The synthesis of (R)-4-Propyldihydrofuran-2(3H)-one is a well-studied area, with various chemical routes developed to ensure high yield and purity. From traditional multi-step chemical syntheses to more modern, stereoselective approaches, researchers and manufacturers continuously seek to optimize these processes. Efficiency, cost-effectiveness, and environmental impact are all considerations in selecting the most appropriate synthetic method. For those looking to secure this vital compound, understanding the available options for buy (R)-4-Propyldihydrofuran-2(3H)-one is essential. NINGBO INNO PHARMCHEM CO., LTD. is one of the suppliers that can provide this pharmaceutical intermediate.
Beyond its direct application in Brivaracetam production, (R)-4-Propyldihydrofuran-2(3H)-one also serves as a valuable building block in broader organic synthesis. Its reactive functional groups and chiral center make it amenable to a range of chemical transformations, opening avenues for the development of other novel compounds. This versatility underscores the importance of such intermediates in driving innovation within medicinal chemistry and drug discovery.
The journey from raw material to finished pharmaceutical product is complex, with each intermediate playing a crucial part. The reliable supply of high-quality (R)-4-Propyldihydrofuran-2(3H)-one, backed by stringent quality control, is vital for pharmaceutical companies to meet global health needs. For researchers and manufacturers in this field, sourcing this compound is a critical step in advancing therapeutic solutions.
Perspectives & Insights
Quantum Pioneer 24
“The compound itself is described as a yellow oily liquid, exhibiting moderate solubility in common organic solvents like chloroform, methanol, and ethanol.”
Bio Explorer X
“This physical characteristic dictates specific handling and storage conditions, typically requiring refrigeration between 2-8°C to maintain its integrity.”
Nano Catalyst AI
“The precise stereochemistry of (R)-4-Propyldihydrofuran-2(3H)-one is not merely an academic detail; it is fundamental to the pharmacological activity of the final drug, Brivaracetam.”