At Ningbo Inno Pharmchem Co., Ltd., we understand the intricate pathways involved in producing vital pharmaceuticals. Today, we focus on a key building block: (1R)-2-[2-(4-nitrophenyl)ethylamino]-1-phenylethanol. This compound plays a pivotal role in the synthesis of Mirabegron, a widely prescribed medication for the treatment of overactive bladder (OAB). The journey from raw materials to a finished pharmaceutical product is complex, and understanding the function of each intermediate is crucial for efficient and high-quality API manufacturing.

(1R)-2-[2-(4-nitrophenyl)ethylamino]-1-phenylethanol, identified by CAS Number 223673-34-5, is a testament to the advancements in pharmaceutical synthesis. Its chemical structure is specifically designed to undergo key transformations that lead to the final Mirabegron molecule. The presence of a nitro group is particularly significant, as it is typically reduced to an amino group in a subsequent step. This nitro group reduction is a common and essential transformation in many API manufacturing processes, enabling the introduction of amine functionalities required for biological activity.

The importance of chiral compounds in modern medicine cannot be overstated. Mirabegron, like many pharmaceuticals, has a specific stereochemical configuration that is critical for its efficacy and safety. The designation '(1R)' in the compound's name signifies its specific chirality at a key carbon atom. This highlights the demand for precise chiral synthesis of APIs, where intermediates with the correct spatial arrangement are paramount. Utilizing intermediates like (1R)-2-[2-(4-nitrophenyl)ethylamino]-1-phenylethanol ensures that the correct enantiomer is built into the final drug product, avoiding potential issues with inactive or even harmful stereoisomers.

The production of high-purity intermediates is a hallmark of quality in the pharmaceutical industry. Our commitment at Ningbo Inno Pharmchem Co., Ltd. is to provide materials that meet rigorous specifications. For (1R)-2-[2-(4-nitrophenyl)ethylamino]-1-phenylethanol, this typically means an assay of ≥98.0%. Achieving such purity is often a result of optimized organic synthesis pathways and meticulous purification techniques. These steps are vital for ensuring that downstream reactions proceed smoothly and that the final API is free from unacceptable levels of impurities.

When considering the purchase of such critical materials, manufacturers often look for reliable suppliers who can guarantee consistent quality and timely delivery. The price and availability of key intermediates directly impact the production costs and market readiness of the final drug. Sourcing high-quality pharmaceutical intermediates is a strategic decision for any drug developer. For those interested in acquiring (1R)-2-[2-(4-nitrophenyl)ethylamino]-1-phenylethanol or similar advanced intermediates, exploring options for buy and purchase from trusted manufacturers like Ningbo Inno Pharmchem Co., Ltd. is a logical step towards a successful drug development pipeline.