In the dynamic landscape of pharmaceutical development, the availability of high-quality chemical intermediates is paramount. Among these, 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile (CAS: 1214377-57-7) has emerged as a compound of significant importance. Its intricate structure and specific chemical properties make it an indispensable building block for a range of therapeutic agents, particularly in the synthesis of advanced pharmaceuticals. This article delves into the characteristics, applications, and overall significance of this pyridine derivative in modern drug manufacturing.

Understanding the Compound: Properties and Purity

5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile is characterized by its molecular formula C7H2BrF3N2 and a molecular weight of approximately 251.00300. It presents as a white crystalline powder, a form that facilitates handling and storage. The compound's chemical profile includes a density of 1.81 g/cm³, a boiling point of 257ºC, and a flash point of 110ºC. Critically, it typically boasts a purity of ≥99.0%, a specification that is non-negotiable in the pharmaceutical industry. This high level of purity ensures that downstream synthesis processes are efficient and that the final drug products meet stringent quality and safety standards. Researchers and manufacturers often seek a reliable 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile supplier to guarantee this level of quality for their critical projects.

Key Applications in Pharmaceutical Synthesis

The primary application of 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile lies in its role as a vital intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Notably, it is a key precursor in the manufacturing of apalutamide, an androgen receptor inhibitor used in the treatment of prostate cancer. The presence of the trifluoromethyl group enhances lipophilicity, which can improve the bioavailability and efficacy of the resulting drug. This makes it an attractive component for drug discovery programs targeting various medical conditions. Sourcing this compound from a reputable CAS 1214377-57-7 manufacturer is crucial for companies aiming for efficiency and success in their drug development pipelines.

Why Purity Matters for Drug Development

The pharmaceutical industry places immense emphasis on the purity of its raw materials and intermediates. Impurities in chemical compounds can lead to unwanted side reactions, reduced product yield, and, most importantly, compromised safety and efficacy of the final drug. 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile, with its consistently high purity, helps mitigate these risks. Manufacturers who buy 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile can be more confident in the predictability and reliability of their synthetic processes. This confidence translates to faster development cycles, reduced rework, and ultimately, quicker market entry for life-saving medications. Working with a trusted trifluoromethyl pyridinecarbonitrile producer ensures that these critical standards are met.

Global Demand and Supply Chain Considerations

The demand for high-quality pharmaceutical intermediates like 5-Bromo-3-(trifluoromethyl)-2-pyridinecarbonitrile is driven by the global pharmaceutical industry's relentless pursuit of innovation and improved healthcare solutions. As research and development continue to advance, the need for reliable chemical building blocks will only intensify. China, with its advanced chemical manufacturing capabilities, plays a significant role in meeting this global demand. Companies looking to secure their supply chains often partner with established manufacturers in the region. For those seeking to purchase this essential compound, understanding the market and identifying a dependable high purity pyridine derivative supplier is a strategic imperative. NINGBO INNO PHARMCHEM CO.,LTD. is committed to meeting these demands with exceptional product quality and reliable service.