In the field of modern organic synthesis, achieving enantioselectivity – the preferential formation of one enantiomer over another – is often paramount, especially in the pharmaceutical and fine chemical industries. Chiral amines are at the forefront of enabling these precise transformations, and (S)-1-phenylethanamine, bearing the CAS number 2627-86-3, is a prime example of such a critical intermediate.

(S)-1-phenylethanamine, also known by synonyms such as L-(-)-α-Phenylethylamine or (S)-α-Methylbenzylamine, is a clear, colorless liquid. Its defining characteristic is its chirality, which allows it to influence the stereochemical outcome of reactions. This makes it an invaluable tool for chemists aiming to synthesize specific chiral compounds with high optical purity. The ability to buy (S)-1-phenylethanamine is fundamental for researchers working in enantioselective synthesis.

The compound’s physical properties, including its melting point of -10°C and boiling point of 187-189°C, along with its 95% minimum purity, provide a solid foundation for its application. These characteristics ensure that it can be readily incorporated into various synthetic protocols, contributing to reliable and reproducible results. The demand for such well-characterized chiral building blocks is high, making the role of (S)-1-phenylethanamine manufacturers and (S)-1-phenylethanamine suppliers indispensable.

The applications of (S)-1-phenylethanamine are diverse, ranging from acting as a chiral resolving agent to serving as a direct participant in chiral synthesis. For instance, it is employed in the one-pot multi-component synthesis of highly substituted chiral pyrroles, a testament to its versatility. This capability highlights its importance not just as a precursor but as an active facilitator in complex molecular construction.

The broader field of chiral building blocks for drug discovery relies heavily on intermediates like (S)-1-phenylethanamine. Its contribution to creating enantiomerically pure compounds is directly linked to the development of safer and more effective pharmaceuticals. Understanding the (S)-1-phenylethanamine applications is key to appreciating its impact on medicinal chemistry and related fields.

In summary, (S)-1-phenylethanamine is a cornerstone in enantioselective synthesis. Its well-defined chiral nature, combined with its practical physical and chemical properties, makes it an essential intermediate for chemists pushing the boundaries of molecular design and synthesis in pursuit of new and improved chemical products.