At NINGBO INNO PHARMCHEM CO.,LTD., we recognize the pivotal role that specific chemical intermediates play in driving innovation across industries. This article focuses on 4-Bromo-2-fluoropyridine (CAS: 128071-98-7), a compound that has proven indispensable in advanced organic synthesis, especially within the demanding field of pharmaceutical development.

4-Bromo-2-fluoropyridine, with its molecular formula C5H3BrFN, is a fascinating molecule characterized by its pyridine core, substituted with both bromine and fluorine atoms. This specific arrangement imparts unique reactivity, making it a highly desirable building block for chemists. Typically appearing as a colorless to light yellow liquid, it possesses a density of around 1.7 g/cm³ and a boiling point at standard pressure of approximately 196°C. These properties are crucial for understanding its behavior in various reaction environments. The CAS 128071-98-7 chemical properties are well-documented, highlighting its utility.

The primary domain where 4-Bromo-2-fluoropyridine shines is as a pharmaceutical intermediate. It is instrumental in the synthesis of Active Pharmaceutical Ingredients (APIs), facilitating the creation of complex molecular structures essential for drug efficacy. Its ability to undergo reactions like the Suzuki-Miyaura cross-coupling is a testament to its versatility, allowing for the precise formation of new carbon-carbon bonds. This makes it an invaluable component in the synthesis of isoquinolinone derivatives and other pharmacologically relevant molecules.

The strategic placement of halogens on the pyridine ring allows for controlled chemical modifications. This feature is highly prized in research and development, where chemists often need to introduce specific functional groups or create particular stereochemical arrangements. The compound's role as a versatile building block cannot be overstated for those engaged in cutting-edge organic chemistry.

The global chemical industry, particularly in the realm of fine chemicals and intermediates, has seen significant growth in Asian manufacturing hubs. Companies seeking to procure materials like 4-Bromo-2-fluoropyridine often look to China for reliable suppliers. Partnering with experienced fine chemical manufacturers in China ensures access to products that meet stringent purity requirements and are available at competitive prices. This strategic sourcing is vital for maintaining efficient production cycles.

When working with such specialized chemicals, understanding the correct handling and storage of halogenated pyridines is critical. Proper storage conditions, such as maintaining a cool, dry environment and using tightly sealed containers, help preserve the chemical's quality and prevent degradation. Adherence to safety protocols is paramount for ensuring the well-being of laboratory personnel and the integrity of the experimental process.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to facilitating scientific discovery by providing access to essential chemical building blocks. Our comprehensive range of intermediates, including 4-Bromo-2-fluoropyridine, supports the critical work of researchers and manufacturers worldwide, helping to advance pharmaceutical innovation and other chemical applications.