In the intricate world of peptide synthesis, the quality and reliability of individual amino acid derivatives are paramount. Among these, Fmoc-Asn-OH stands out as a cornerstone reagent, crucial for the accurate and efficient construction of complex peptide chains. This article, brought to you by NINGBO INNO PHARMCHEM CO.,LTD., delves into the significance of Fmoc-Asn-OH, exploring its chemical characteristics and its wide-ranging applications in scientific research.

Fmoc-Asn-OH, chemically known as N-alpha-Fmoc-L-asparagine, is a derivative of the naturally occurring amino acid L-asparagine. The 'Fmoc' (9-fluorenylmethoxycarbonyl) group serves as a temporary protecting group for the alpha-amino function. This protection is vital in solid-phase peptide synthesis (SPPS) as it prevents unwanted reactions at the amino terminus during the coupling of subsequent amino acids. The deprotection of the Fmoc group, typically achieved with a mild base like piperidine, is a key step that allows for the continuous elongation of the peptide chain. Understanding the Fmoc-Asn-OH chemical properties is essential for optimizing these synthesis processes.

The CAS number for Fmoc-Asn-OH is 71989-16-7, a unique identifier that helps researchers pinpoint the exact compound they need. The availability of reliable Fmoc-Asn-OH CAS number and suppliers is critical for maintaining the integrity of experimental workflows. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted source for high-quality Fmoc-Asn-OH, ensuring that researchers have access to a consistent and pure product.

The primary application of Fmoc-Asn-OH lies in Fmoc-Asn-OH synthesis applications, particularly within SPPS. Its role is to introduce the asparagine residue into the growing peptide sequence. Asparagine is a polar, uncharged amino acid that plays significant roles in protein structure and function, often involved in hydrogen bonding and stabilizing peptide conformations. Therefore, its accurate incorporation is crucial for synthesizing peptides that mimic biological functions or possess therapeutic properties.

The benefits of using Fmoc-Asn-OH in SPPS are manifold. Firstly, its Fmoc protection strategy is compatible with mild cleavage conditions, preserving the integrity of acid-labile side-chain protecting groups. Secondly, the high purity of Fmoc-Asn-OH, typically greater than 98%, minimizes side reactions and ensures a higher yield of the desired peptide. This high purity is a testament to advanced manufacturing processes, a hallmark of NINGBO INNO PHARMCHEM CO.,LTD.

Beyond its direct role in peptide synthesis, Fmoc-Asn-OH is a vital reagent in drug discovery and proteomics. Researchers utilize it to synthesize peptide-based drugs, diagnostic tools, and to study protein modifications. The ability to precisely assemble peptides with specific amino acid sequences allows for the development of novel therapeutic agents and a deeper understanding of biological processes.

In conclusion, Fmoc-Asn-OH is more than just a chemical reagent; it is an enabler of scientific discovery. Its reliable performance, facilitated by strict quality control and sourcing from reputable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., underscores its importance in advancing peptide-based research and development.