The Indispensable Role of (1S,2S)-(1-Benzyl-3-Chloro-2-Hydroxypropyl)Carbamic Acid Tert-Butyl Ester in HIV Treatment
In the relentless pursuit of effective treatments for HIV/AIDS, pharmaceutical intermediates stand as the silent architects of life-saving medications. Among these, (1S,2S)-(1-Benzyl-3-Chloro-2-Hydroxypropyl)Carbamic Acid Tert-Butyl Ester, identified by its CAS number 165727-45-7, plays a pivotal role. This compound is not merely a chemical substance; it is a cornerstone in the synthesis of Darunavir, a potent protease inhibitor that has significantly advanced HIV therapy. Understanding its properties and applications is crucial for appreciating the complexities of modern drug development and supply chains.
The primary significance of (1S,2S)-(1-Benzyl-3-Chloro-2-Hydroxypropyl)Carbamic Acid Tert-Butyl Ester lies in its direct contribution to the production of Darunavir. Darunavir is a critical component in the management of HIV infection, particularly for patients with drug-resistant strains. The synthesis of such a complex molecule requires highly specific and pure intermediates, and this compound fits that description perfectly. Its molecular formula, C15H20ClNO3, and molecular weight of 299.79308 hint at its intricate structure, which is meticulously designed to facilitate its transformation into the active pharmaceutical ingredient.
Manufacturers typically ensure that this compound meets stringent quality standards, often with an assay exceeding 98.0% and a moisture content below 0.5%. These specifications are vital for ensuring the reliability and efficiency of the downstream synthesis. The production processes for this intermediate often involve advanced chemical reactions and rigorous quality control to maintain the necessary purity and chiral integrity. For companies seeking to buy (1S,2S)-(1-Benzyl-3-Chloro-2-Hydroxypropyl)Carbamic Acid Tert-Butyl Ester, partnering with a reliable CAS 165727-45-7 supplier is paramount to the success of their pharmaceutical manufacturing operations.
The compound's utility extends beyond its direct role in Darunavir synthesis. Its inherent chemical stability and reactivity make it a valuable starting material or intermediate in various other synthetic pathways within medicinal chemistry. Researchers often utilize such compounds for the development of novel therapeutics, leveraging their precise structural features for targeted molecular design. The increasing global demand for effective HIV treatments directly translates into a sustained need for high-quality intermediates like this one, making its availability and consistent supply critical for the pharmaceutical industry.
In essence, (1S,2S)-(1-Benzyl-3-Chloro-2-Hydroxypropyl)Carbamic Acid Tert-Butyl Ester exemplifies the sophisticated chemistry that underpins modern medicine. It is a testament to the intricate processes and dedicated research involved in producing essential drugs that improve and save lives worldwide. As the pharmaceutical landscape continues to evolve, intermediates like these will remain foundational to our ability to combat complex diseases.
Perspectives & Insights
Future Origin 2025
“In essence, (1S,2S)-(1-Benzyl-3-Chloro-2-Hydroxypropyl)Carbamic Acid Tert-Butyl Ester exemplifies the sophisticated chemistry that underpins modern medicine.”
Core Analyst 01
“It is a testament to the intricate processes and dedicated research involved in producing essential drugs that improve and save lives worldwide.”
Silicon Seeker One
“As the pharmaceutical landscape continues to evolve, intermediates like these will remain foundational to our ability to combat complex diseases.”