In the intricate landscape of pharmaceutical manufacturing, the quality and availability of key intermediates are paramount. Among these essential compounds, (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride (CAS: 1062580-52-2) stands out as a critical building block, particularly for the synthesis of Tofacitinib. This pharmaceutical intermediate plays a pivotal role in the production of a drug that has significantly advanced the treatment of autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

NINGBO INNO PHARMCHEM CO.,LTD. recognizes the importance of this compound and focuses on delivering high-purity products that meet stringent pharmaceutical standards. The compound, often referred to by its synonyms like cis-n-benzyl-3-methylamino-4-methyl-piperidine dihydrochloride, is characterized by its white powder appearance, a purity of ≥98%, and a low water content (≤0.5%). These specifications are crucial for ensuring the efficacy and safety of the final Tofacitinib drug product. The meticulous production process, backed by advanced synthesis capabilities, ensures that each batch meets the required quality benchmarks.

The application of (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride is primarily as an intermediate in the synthesis of Tofacitinib. The precise stereochemistry, denoted by (3R,4R), is vital for the molecule's biological activity. Pharmaceutical companies rely on dependable suppliers to maintain a consistent supply chain for this intermediate, enabling uninterrupted production of Tofacitinib. Understanding the market for this compound, including pricing and availability from various manufacturers, is key for procurement professionals. For companies looking to buy this critical intermediate, researching Tofacitinib intermediate synthesis methods and identifying reliable Tofacitinib intermediate suppliers is a strategic imperative.

The chemical properties of (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride, including its molecular formula (C14H24Cl2N2) and molecular weight (291.26), are well-defined. Its stability, indicated by a melting point of 219-220°C and a flash point of 200°C, makes it suitable for storage and handling in industrial settings. When considering the purchase of this compound, understanding the technical specifications and ensuring compliance with regulatory standards is essential. Collaborating with experienced chemical synthesis manufacturers who can provide custom synthesis services if needed, further strengthens the supply chain.

As a significant player in the pharmaceutical supply chain, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride. By focusing on rigorous quality control and efficient production, we support the global pharmaceutical industry in its mission to develop and deliver life-changing treatments. For those seeking this crucial intermediate, engaging with a reputable (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride manufacturer is the first step towards ensuring the success of their pharmaceutical projects.