In the intricate world of pharmaceutical manufacturing, the quality and availability of key intermediates directly impact the success of drug production. One such critical compound is Ethyl Trifluoroacetate (CAS: 383-63-1), a colorless transparent liquid that serves as an indispensable building block in the synthesis of Celecoxib, a widely recognized nonsteroidal anti-inflammatory drug (NSAID). Understanding the properties and applications of this chemical is crucial for manufacturers aiming for precision and efficacy in their formulations.

Ethyl Trifluoroacetate, also known by synonyms such as Ethyl 2,2,2-trifluoroacetate or Trifluoroacetic Acid Ethyl Ester, possesses a unique molecular structure (C4H5F3O2) with a molecular weight of 142.077. Its physical characteristics, including a boiling point of 61.5±3.0 °C and a flash point of -1.1±0.0 °C, make it manageable under various reaction conditions. Crucially, its assay, typically ≥98.0% by GC, signifies a high level of purity essential for pharmaceutical synthesis, minimizing unwanted byproducts and ensuring the integrity of the final drug.

The primary significance of Ethyl Trifluoroacetate lies in its role as an intermediate for Celecoxib. The incorporation of the trifluoroacetyl group from Ethyl Trifluoroacetate into the molecular framework of Celecoxib is a key step in its synthesis. This fluorinated moiety often enhances the metabolic stability and lipophilicity of the drug, contributing to its pharmacological profile. For companies seeking to purchase Ethyl Trifluoroacetate, sourcing from a reputable manufacturer in China offers a distinct advantage in terms of cost-effectiveness and supply chain reliability. We, at NINGBO INNO PHARMCHEM CO.,LTD., are dedicated to providing high-purity Ethyl Trifluoroacetate, meeting the stringent demands of the pharmaceutical industry. Our commitment ensures that manufacturers can reliably buy Ethyl Trifluoroacetate for their Celecoxib production needs.

Beyond its direct link to Celecoxib, Ethyl Trifluoroacetate is a versatile reagent in broader organic synthesis. It facilitates the introduction of fluorine atoms and trifluoromethyl groups into various organic molecules. This capability is highly valued in the development of new pharmaceuticals and agrochemicals, as fluorination can significantly improve a compound's bioactivity, stability, and efficacy. Researchers and manufacturers looking for specialized celecoxib intermediates or custom synthesis celecoxib intermediates often rely on compounds like Ethyl Trifluoroacetate to achieve desired molecular modifications.

The demand for high-purity pharmaceutical intermediates is constantly growing, driven by the need for safer and more effective medications. As a dedicated ethyl trifluoroacetate manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. prioritizes quality control and efficient production processes. We understand the critical nature of these chemicals and strive to be a trusted partner for businesses worldwide. Whether you are looking for Ethyl Trifluoroacetate in bulk quantities or require custom solutions, our expertise and infrastructure are designed to meet your specific requirements, ensuring timely delivery and consistent quality.