The Molecular Architecture: Understanding N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on providing not just chemicals, but critical molecular building blocks for the pharmaceutical industry. Understanding the intricate details of these compounds is essential for successful synthesis, and this article focuses on the molecular architecture of N-[5-(diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide, a crucial intermediate for Rosuvastatin.
The chemical name itself, N-[5-(diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide, reveals a complex structure. It features a pyrimidine core, substituted with an isopropyl group, a fluorophenyl group, and importantly, a diphenylphosphinoylmethyl moiety. This phosphine oxide group is characteristic of the molecule and plays a significant role in its reactivity during synthetic processes. The presence of the methylmethanesulfonamide group further defines its chemical identity.
The chemical synthesis of Rosuvastatin leverages the specific functionalities within this molecule. The phosphine oxide group, for instance, can be involved in various synthetic transformations, acting as a handle for further elaboration or as a crucial part of the final drug's scaffold. The fluorophenyl substituent contributes to the overall electronic properties of the molecule, which can influence its interaction in biological systems and its behavior during synthesis. Understanding these structural nuances is key for chemists working on Rosuvastatin intermediate synthesis.
As a physical substance, our N-[5-(diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide is characterized by its appearance as a white to off-white powder. This physical form, coupled with specifications such as high purity (≥98.0%), low water content, and controlled loss on drying, ensures its suitability for demanding pharmaceutical applications. When you buy N-[5-(diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide from us, you receive a compound that has been meticulously synthesized and characterized.
The molecular weight of this compound is approximately 537.59 g/mol, indicating a substantial and complex molecule. Its precise chemical structure is critical for its function as a Rosuvastatin intermediate. The careful arrangement of its constituent atoms and functional groups dictates its reactivity, solubility, and stability, all of which are vital considerations in the pharmaceutical intermediate supply chain.
At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing high-quality intermediates that are chemically sound and reliable. Our expertise in synthesizing compounds like N-[5-(diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide supports the advancement of pharmaceutical manufacturing and ultimately contributes to better healthcare outcomes globally.
Perspectives & Insights
Alpha Spark Labs
“The presence of the methylmethanesulfonamide group further defines its chemical identity.”
Future Pioneer 88
“The chemical synthesis of Rosuvastatin leverages the specific functionalities within this molecule.”
Core Explorer Pro
“The phosphine oxide group, for instance, can be involved in various synthetic transformations, acting as a handle for further elaboration or as a crucial part of the final drug's scaffold.”