Niclosamide, a compound with a rich history in treating parasitic infections, is now at the forefront of groundbreaking medical research. Originally recognized for its efficacy as an anthelmintic, particularly against tapeworms, and its use as a molluscicide, Niclosamide's complex biological profile is revealing new therapeutic avenues.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality chemical compounds that fuel scientific discovery. Our understanding of Niclosamide chemical properties is crucial for researchers exploring its diverse applications. With its CAS number 50-65-7 and molecular formula C13H8Cl2N2O4, Niclosamide presents a well-defined structure that underpins its varied activities.

One of the most exciting areas of research involves Niclosamide's potent ability to inhibit the STAT3 signaling pathway. STAT3 (Signal Transducer and Activator of Transcription 3) is a protein that plays a critical role in cell growth, survival, and immune response. Aberrant STAT3 activation is frequently observed in various cancers, making it a prime target for oncological therapies. Research indicates that Niclosamide can effectively block STAT3 activation, offering a promising strategy for developing new cancer treatments. The exploration of Niclosamide anticancer activity is a testament to its potential as a repurposed drug.

Furthermore, Niclosamide has demonstrated efficacy as an autophagy inducer. Autophagy is a cellular process that removes damaged components and recycles cellular material. While crucial for cell survival under stress, dysregulated autophagy can contribute to diseases like cancer and neurodegeneration. By inducing autophagy, Niclosamide may offer therapeutic benefits in contexts where this process needs to be stimulated. Understanding Niclosamide autophagy inducer properties is vital for its application in cellular research and disease management.

The established use of Niclosamide as an anthelmintic, combating parasitic worm infections, remains a significant aspect of its application. Its mechanism involves interfering with the energy metabolism of parasites, making it an effective treatment. Additionally, its role as a molluscicide aids in controlling disease vectors. The consistent quality of Niclosamide supplied by NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers and healthcare providers can rely on its performance for established and novel applications.

In conclusion, Niclosamide is far more than just an anthelmintic. Its diverse biological activities, including Niclosamide STAT3 inhibition and autophagy induction, position it as a valuable compound for ongoing research in oncology, infectious diseases, and cellular biology. NINGBO INNO PHARMCHEM CO.,LTD. is proud to support these advancements by providing high-purity Niclosamide.