At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing the chemical building blocks that drive innovation, especially within the dynamic field of pharmaceutical research and development. One such indispensable compound is 4-Ethynylaniline, identified by its CAS number 14235-81-5. This molecule, often referred to by its synonyms like p-ethynylaniline or 4-aminophenylacetylene, is a terminal alkyne that has garnered significant attention for its crucial role in the synthesis of various therapeutic agents.

The unique structure of 4-ethynylaniline, featuring both an amine group and a terminal alkyne, makes it an exceptionally versatile intermediate. Its primary application in drug discovery lies in its utility in 'click chemistry', specifically the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. This highly efficient and reliable reaction allows for the facile formation of stable triazole rings, which are common structural motifs in many biologically active compounds. The ability to reliably perform these click chemistry reactions using high-purity 4-ethynylaniline, as supplied by NINGBO INNO PHARMCHEM CO.,LTD., accelerates the discovery and development of new drug candidates.

One of the most prominent examples highlighting the importance of 4-ethynylaniline is its use in the synthesis of erlotinib. Erlotinib is a targeted therapy drug used in the treatment of certain types of lung cancer and pancreatic cancer. As a key pharmaceutical intermediate, the consistent quality and availability of 4-ethynylaniline are paramount for manufacturers of erlotinib and similar oncology drugs. NINGBO INNO PHARMCHEM CO.,LTD. ensures a steady supply chain and stringent quality control for this vital chemical, supporting the production of life-saving medications.

Beyond its role in synthesizing established drugs, 4-ethynylaniline serves as a valuable starting material for exploring novel chemical entities. Medicinal chemists frequently employ it to create diverse libraries of compounds for screening against various biological targets. The versatility of the molecule allows for its incorporation into complex molecular architectures, potentially leading to the discovery of new treatments for a wide range of diseases. The demand for reliable suppliers who can offer this compound with excellent purity, such as NINGBO INNO PHARMCHEM CO.,LTD., remains high.

For researchers and manufacturers seeking to procure 4-ethynylaniline for their drug discovery programs or active pharmaceutical ingredient (API) synthesis, partnering with a reputable supplier is essential. NINGBO INNO PHARMCHEM CO.,LTD. is committed to meeting the exacting standards of the pharmaceutical industry, ensuring that our 4-ethynylaniline, readily available for purchase, contributes to the successful development and manufacturing of effective medicines. We understand the critical nature of our products and strive to provide exceptional service and product quality to facilitate your research and commercialization efforts.

By consistently delivering high-quality 4-ethynylaniline, NINGBO INNO PHARMCHEM CO.,LTD. plays a crucial role in enabling breakthroughs in drug development, supporting the creation of innovative therapies that improve patient outcomes worldwide. Consider NINGBO INNO PHARMCHEM CO.,LTD. for your next project requiring this essential pharmaceutical intermediate.