NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of high-quality chemical intermediates. Among its extensive catalog, 3-Amino-[1,1'-Biphenyl]-4-ol stands out as a particularly versatile compound with significant applications across various industries. This article delves into the chemical properties, synthesis, and extensive utility of this important molecule.

Understanding 3-Amino-[1,1'-Biphenyl]-4-ol (CAS 1134-36-7)

3-Amino-[1,1'-Biphenyl]-4-ol, also known by synonyms such as 3-Amino-4-hydroxybiphenyl or 2-Amino-4-phenylphenol, is an organic compound characterized by its biphenyl structure with appended amino and hydroxyl groups. This molecular architecture makes it an ideal building block for creating more complex chemical structures. Its CAS number, 1134-36-7, uniquely identifies this substance within the global chemical registry.

Synthesis Pathways and Optimization

NINGBO INNO PHARMCHEM CO.,LTD. employs optimized synthesis routes to ensure the high purity and consistent supply of 3-Amino-[1,1'-Biphenyl]-4-ol. While several methods exist, common approaches include the reduction of nitro precursors. For instance, catalytic hydrogenation of 2-nitro-4-phenylphenol using catalysts like Palladium on Carbon (Pd-C) or reduction with agents such as sodium borohydride are effective. Optimization often involves precise control of reaction temperature, typically between 25–50°C, and careful selection of solvents like ethanol or tetrahydrofuran to maximize yield. Post-synthesis purification, often through recrystallization or column chromatography, is crucial to achieve the high purity required for research and industrial applications, with purity levels frequently exceeding 97%.

Key Applications Across Industries

The versatility of 3-Amino-[1,1'-Biphenyl]-4-ol is evident in its widespread applications:

  • Organic Synthesis: It serves as a fundamental building block, enabling chemists to introduce specific functionalities and construct complex organic molecules. Researchers often search for organic synthesis building blocks to facilitate their innovative projects.
  • Pharmaceuticals: As a crucial pharmaceutical precursor, it plays a role in the development of new drug candidates, particularly in areas like anti-cancer research. Its structural features are valuable for designing molecules with desired biological activities.
  • Dyes and Colorants: The compound is an important dye intermediate, used in the synthesis of various colorants, including azo dyes. Its chemical structure lends itself to the creation of stable and vibrant pigments.
  • Agrochemicals: In the agrochemical sector, it is utilized in the synthesis of herbicides and pesticides, contributing to the development of more effective crop protection agents. Understanding agrochemical synthesis is vital for modern agriculture.
  • Biomedical Research: Beyond synthesis, it finds application in biomedical research as an internal standard for studying enzymatic activities. This is particularly relevant in cancer research where metabolic pathways are investigated.
  • Forensic Science: Its ability to form complexes with certain metal ions makes it a useful reagent for toxicological analyses in forensic investigations, aiding in the detection of trace substances.

When looking to buy 3-Amino-[1,1'-Biphenyl]-4-ol, NINGBO INNO PHARMCHEM CO.,LTD. offers reliable sourcing and competitive pricing, ensuring researchers and manufacturers can access this essential chemical without compromising on quality. The company’s commitment to purity and efficiency makes it a trusted supplier for all your chemical intermediate needs.