The Role of 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate in Darifenacin Production
NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide an in-depth look at 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate, a compound with significant implications in the pharmaceutical industry, particularly in the context of Darifenacin synthesis. Understanding the nuances of this chemical entity, identified by CAS number 134002-26-9, is vital for ensuring product quality, regulatory compliance, and the development of effective therapeutic agents.
As a critical component in the multi-step synthesis of Darifenacin, 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate plays a dual role. Primarily, it functions as a key intermediate, meaning its precise formation and purification are essential for the successful production of the final active pharmaceutical ingredient (API). Any deviations in its quality or yield can directly impact the efficiency and outcome of the entire manufacturing process. This highlights the importance of rigorous quality control measures at every stage, aligning with stringent pharmaceutical quality control standards.
Furthermore, this compound is also recognized as a significant impurity that can arise during the synthesis of Darifenacin. Identifying and quantifying such impurities is a cornerstone of pharmaceutical quality assurance. NINGBO INNO PHARMCHEM CO.,LTD. places a strong emphasis on managing and controlling these impurities, ensuring that the final drug product meets all safety and efficacy requirements. The study of such impurities is a fundamental aspect of Darifenacin synthesis and impurities research.
Beyond its role in Darifenacin production, 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate is also noted for its pharmacological properties. It acts as a muscarinic receptor antagonist, a class of compounds that are crucial in treating a variety of medical conditions, most notably overactive bladder, the primary indication for Darifenacin. This intrinsic activity suggests potential for its use in other therapeutic areas or as a lead compound for further drug discovery. This intrinsic activity underscores the value of research into muscarinic receptor antagonists in pharma.
The meticulous control over the production of intermediates like 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate is a testament to the sophisticated nature of modern pharmaceutical manufacturing. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality intermediates that support the global pharmaceutical supply chain. The commitment to excellence in fine chemical sourcing and application ensures that our clients receive materials that meet the highest industry standards, facilitating the development of life-changing medicines.
Perspectives & Insights
Future Origin 2025
“As a critical component in the multi-step synthesis of Darifenacin, 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate plays a dual role.”
Core Analyst 01
“Primarily, it functions as a key intermediate, meaning its precise formation and purification are essential for the successful production of the final active pharmaceutical ingredient (API).”
Silicon Seeker One
“Any deviations in its quality or yield can directly impact the efficiency and outcome of the entire manufacturing process.”