In the intricate world of pharmaceutical manufacturing, specific chemical compounds serve as the foundational building blocks for life-saving medications. Among these, 5-Bromo-2-chloropyrimidine stands out as a crucial intermediate, particularly in the synthesis of Macitentan. This compound, identified by CAS number 32779-36-5, is a testament to the precision required in modern drug development. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying high-quality chemical intermediates like 5-Bromo-2-chloropyrimidine to the global pharmaceutical industry.

The primary application of 5-Bromo-2-chloropyrimidine lies in its indispensable role in the production of Macitentan. Macitentan is an endothelin receptor antagonist approved for the treatment of pulmonary arterial hypertension (PAH), a severe condition affecting the arteries of the lungs and the right side of the heart. The synthesis of such a complex molecule requires intermediates with specific structural features and high purity, which 5-Bromo-2-chloropyrimidine reliably provides. Understanding the chemical synthesis routes for Macitentan using 5-bromo-2-chloropyrimidine is vital for manufacturers aiming for efficient and cost-effective production.

The chemical properties of 5-Bromo-2-chloropyrimidine, including its molecular formula C4H2BrClN2 and a molecular weight of 193.43, make it an ideal reactant for various chemical transformations. It typically appears as an off-white to white powder with a purity often exceeding 98%. Its utility extends beyond Macitentan, as it is also employed in various cross-coupling reactions. These reactions are fundamental in modern organic synthesis, allowing chemists to form new carbon-carbon bonds and construct complex molecular architectures. This versatility makes 5-Bromo-2-chloropyrimidine a valuable asset for chemical building blocks online and for researchers exploring new therapeutic agents.

The demand for reliable suppliers of macitentan intermediate supplier is high, and companies like NINGBO INNO PHARMCHEM CO.,LTD. play a critical role in meeting this demand. By offering high-purity 5-bromo-2-chloropyrimidine CAS 32779-36-5, they ensure that pharmaceutical companies can proceed with their manufacturing processes without compromising on quality. The availability of such essential pharmaceutical building blocks online facilitates smoother drug development pipelines.

In conclusion, 5-Bromo-2-chloropyrimidine is more than just a chemical compound; it is a critical link in the chain of life-saving drug production. Its precise chemical structure and high purity are indispensable for the synthesis of Macitentan and other APIs. NINGBO INNO PHARMCHEM CO.,LTD. remains committed to providing these essential components, thereby contributing significantly to advancements in healthcare and the fight against serious medical conditions like pulmonary arterial hypertension. The continued availability of this compound supports the ongoing efforts in synthesis of macitentan active pharmaceutical ingredient.