The Role of Carboxymethyl Starch Sodium in Enhancing Tablet Formulations
In the intricate process of pharmaceutical formulation, the choice of excipients profoundly influences the performance and stability of the final drug product. Carboxymethyl Starch Sodium (CMSS), also known as Sodium Starch Glycolate (SSG) and identified by CAS No. 9063-38-1, is a highly effective excipient that plays a crucial role in tablet manufacturing. NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality CMSS, recognized for its exceptional properties that enhance tablet quality and drug delivery.
A primary benefit of CMSS is its ability to act as a superior disintegrant. As a sodium carboxymethyl starch tablet disintegrant, it exhibits remarkable swelling properties when exposed to moisture. This rapid swelling creates internal stress within the tablet, leading to its quick fragmentation into smaller particles. This disintegration is essential for the immediate release of the active pharmaceutical ingredient (API) into the gastrointestinal tract, facilitating prompt absorption and therapeutic action. The efficacy of CMSS in promoting rapid disintegration makes it indispensable for many immediate-release formulations.
Furthermore, CMSS contributes significantly to improving the physical characteristics of tablets. It helps in improve tablet hardness disintegrant effects, allowing for the production of tablets that are both hard enough to withstand handling and processing, yet still capable of disintegrating rapidly. This balanced performance ensures that tablets maintain their integrity throughout their shelf life while delivering the API effectively when administered. The dual action of enhancing hardness and ensuring disintegration makes CMSS a highly sought-after excipient.
The utility of CMSS extends beyond tablet formulations. It also functions effectively as a suspension aid for liquid preparations. In liquid dosage forms, CMSS helps to maintain the homogeneity of suspensions by preventing the settling of solid particles. This is crucial for ensuring that each dose administered contains the correct amount of API, thereby maintaining therapeutic efficacy and patient safety. The role of sodium starch glycolate pharmaceutical excipient as a suspension aid highlights its broad applicability in pharmaceutical manufacturing.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying a medicine grade starch ether that meets stringent international quality standards. Our Carboxymethyl Starch Sodium is a reliable chemical reagent that pharmaceutical manufacturers can trust for consistent performance and safety. By incorporating CMSS into their formulations, companies can achieve improved tablet disintegration, enhanced physical strength, and stable liquid preparations, leading to better drug products and improved patient outcomes. The advanced properties of CMSS make it a key ingredient for pharmaceutical companies aiming for excellence in their product development.
Perspectives & Insights
Data Seeker X
“In the intricate process of pharmaceutical formulation, the choice of excipients profoundly influences the performance and stability of the final drug product.”
Chem Reader AI
“Carboxymethyl Starch Sodium (CMSS), also known as Sodium Starch Glycolate (SSG) and identified by CAS No.”
Agile Vision 2025
“9063-38-1, is a highly effective excipient that plays a crucial role in tablet manufacturing.”