Acetaminophen, known globally for its analgesic and antipyretic properties, is one of the most widely used medications. However, like all synthesized pharmaceutical compounds, it is subject to rigorous purity testing to ensure safety and efficacy. A key aspect of this testing involves identifying and quantifying related substances or impurities that may form during synthesis or degradation. One such impurity, 4-Propionamidophenol (CAS 1693-37-4), also known as Acetaminophen Impurity B, is of significant scientific interest. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality standards for such compounds.

Chemically, 4-Propionamidophenol has the molecular formula C9H11NO2 and a molecular weight of 165.19. It presents as a pale purple solid with a melting point typically around 170-172°C. Its structure is closely related to Acetaminophen, which is N-(4-hydroxyphenyl)acetamide. The difference lies in the propionyl group instead of the acetyl group attached to the amide nitrogen. This structural similarity means that analytical techniques like HPLC must be sensitive enough to differentiate between Acetaminophen and its impurities, including 4-Propionamidophenol.

The scientific importance of 4-Propionamidophenol stems from its role as a marker in the Acetaminophen manufacturing process. Its presence, even in trace amounts, can indicate specific synthetic pathways or potential degradation mechanisms. Pharmaceutical scientists use it as a reference standard to develop and validate analytical methods designed to detect and quantify it. This validation process ensures that the analytical methods used are specific, accurate, and reliable, meeting the high standards required by regulatory bodies. NINGBO INNO PHARMCHEM CO.,LTD. contributes to this scientific effort by supplying a well-characterized form of this impurity.

Understanding the chemical behavior and analytical characteristics of 4-Propionamidophenol is fundamental for quality assurance in the Acetaminophen industry. By providing this critical reference material, NINGBO INNO PHARMCHEM CO.,LTD. enables researchers and QC professionals to conduct thorough impurity profiling, ensuring that Acetaminophen products meet the stringent quality and safety regulations globally. This scientific foundation is what guarantees the consistent quality of this essential medication.