In the intricate world of pharmaceutical manufacturing, certain chemical intermediates stand out due to their indispensable role in producing life-saving medications. One such compound is (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride, a critical building block for the widely used antiplatelet drug, Ticagrelor. Understanding the importance of this intermediate, its properties, and the sourcing considerations is vital for drug developers and manufacturers worldwide.

(1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride, identified by its CAS number 1156491-10-9, is a precisely engineered molecule essential for creating Ticagrelor. Ticagrelor is a P2Y12 receptor antagonist that plays a pivotal role in preventing thrombotic events, such as heart attacks and strokes, in individuals with acute coronary syndromes. The efficacy of Ticagrelor is intrinsically linked to the exact stereochemical configuration of its intermediates, making the specific (1R,2S) form of this cyclopropanamine derivative non-negotiable for quality drug production.

The chemical profile of (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride is characterized by its appearance as a white to yellow powder, with a molecular formula of C9H10ClF2N and a molecular weight of 205.632. This high purity, often specified as ≥98.0%, ensures that downstream synthesis processes yield a final drug product that meets stringent regulatory standards. The compound’s stability is maintained when stored under appropriate conditions, typically in a cool, ventilated environment, which is a crucial consideration for inventory management and product integrity.

The demand for high-quality pharmaceutical intermediates like (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride has led to a specialized market where reliability and quality assurance are paramount. Sourcing this intermediate from established manufacturers, such as NINGBO INNO PHARMCHEM CO.,LTD., offers significant advantages. These suppliers often possess advanced synthesis capabilities, rigorous quality control systems, and the flexibility to meet varied packaging and quantity requirements. For companies seeking to buy this compound, understanding the pricing and availability from a trusted supplier in China can be a strategic move in managing production costs and ensuring timely delivery.

The importance of this intermediate underscores the broader trend in the pharmaceutical industry towards specialized fine chemicals and complex intermediates. NINGBO INNO PHARMCHEM CO.,LTD. exemplifies a commitment to these sectors, offering not just this key intermediate but also a range of services including custom synthesis and process development. This integrated approach supports pharmaceutical companies in accelerating their drug development timelines and bringing critical treatments to market more efficiently. For those in need of a dependable supplier for (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride, NINGBO INNO PHARMCHEM CO.,LTD. provides the expertise and infrastructure necessary to meet the demanding requirements of pharmaceutical manufacturing.

In conclusion, (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride is more than just a chemical compound; it is a critical enabler of modern cardiovascular therapies. Its precise synthesis, high purity, and reliable sourcing are fundamental to the successful production of Ticagrelor, contributing significantly to patient health and well-being.