In the complex world of pharmaceutical synthesis, specific chemical compounds serve as fundamental building blocks that enable the creation of advanced therapeutic agents. (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine, identified by its CAS number 863329-66-2, is one such critical molecule. NINGBO INNO PHARMCHEM CO.,LTD. recognizes its importance as a high-purity pharmaceutical intermediate, particularly in the synthesis of antiviral drugs like Sofosbuvir.

The molecule itself, characterized by its formula C10H13FN2O5 and molecular weight of 260.21900, is a derivative of uridine. Its physical presentation as a white to off-white powder, with a melting point of 237-238°C, speaks to its stability and suitability for handling in pharmaceutical manufacturing. Crucially, its purity level, consistently meeting or exceeding 98.0%, is non-negotiable for its application in creating safe and effective medications. This dedication to quality aligns with the core principles of pharmaceutical intermediate manufacturing, where precision is key.

The primary significance of (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine lies in its role as a Sofosbuvir synthesis intermediate. Sofosbuvir, a potent inhibitor of the Hepatitis C virus (HCV) RNA polymerase, has transformed the treatment landscape for Hepatitis C. The reliable and efficient synthesis of Sofosbuvir depends directly on the quality and availability of its precursor, making this nucleoside analog an indispensable component. The demand for such intermediates fuels the need for robust Antiviral Nucleoside Analogs Synthesis processes.

Moreover, (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine serves as a valuable tool in broader nucleoside analog for antiviral research efforts. Scientists utilize it to explore new pathways for inhibiting viral replication and to understand the metabolic activation of such compounds. As a known HCV replication inhibitor metabolite, it offers insights into the mechanisms by which these drugs exert their effects, guiding the design of future antivirals. The continuous investigation into these mechanisms is vital for advancing Hepatitis C Virus (HCV) Therapeutics Research and developing treatments for other viral diseases.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the pharmaceutical industry by providing access to essential building blocks like (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine. Our focus on quality assurance and efficient production ensures that our clients can rely on us for their critical intermediate needs, thereby contributing to the development of life-changing medications.