NINGBO INNO PHARMCHEM CO.,LTD. presents insights into 4-Bromo-2-fluoropyridine (CAS: 128071-98-7), a compound that holds considerable importance in modern chemical synthesis, particularly as a pharmaceutical intermediate. This article highlights its fundamental properties and diverse applications.

4-Bromo-2-fluoropyridine, also referred to as 2-Fluoro-4-bromopyridine, is a pyridine derivative with the molecular formula C5H3BrFN and a molecular weight of 175.99. Its physical state is typically described as a colorless to light yellow liquid. Key physical properties include a density of approximately 1.7 g/cm³ and a boiling point around 196°C at 760 mmHg, along with a flash point of about 72°C. These characteristics define its handling and reactivity profiles. A thorough understanding of these CAS 128071-98-7 chemical properties is crucial for its effective application.

The compound's foremost role is as a pharmaceutical intermediate. It serves as a vital component in the synthesis of Active Pharmaceutical Ingredients (APIs), allowing for the construction of intricate molecular frameworks essential for drug efficacy. Its utility is particularly evident in cross-coupling reactions, such as the Suzuki-Miyaura reaction, where it facilitates the formation of new carbon-carbon bonds. This makes it a key reagent for the synthesis of isoquinolinone derivatives and other pharmacologically active compounds.

As a versatile organic building block, 4-Bromo-2-fluoropyridine is also utilized in broader organic synthesis research. Its precisely positioned halogens enable targeted chemical modifications, supporting the development of novel chemical entities and advanced synthetic strategies. The compound's predictable reactivity makes it a reliable choice for researchers in academic and industrial settings.

The global chemical supply chain often features specialized manufacturing hubs, with China being a prominent one for fine chemicals. For businesses requiring a steady supply of 4-Bromo-2-fluoropyridine, engaging with fine chemical manufacturers in China offers a strategic advantage in terms of both quality and cost. The industry places a strong emphasis on proper handling and storage of halogenated pyridines to ensure chemical integrity and safety.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying the chemical industry with essential intermediates. Our provision of 4-Bromo-2-fluoropyridine supports the vital work of researchers and manufacturers, contributing to advancements in pharmaceuticals and other critical chemical sectors.