Disalicylimide, identified by the CAS number 1972-71-0, is a compound of significant importance within the pharmaceutical industry. Its role as a key intermediate and a reference standard for specific drug impurities underscores the need for robust chemical synthesis pathways. Understanding these pathways is crucial for manufacturers aiming to produce high-quality Disalicylimide consistently.

The synthesis of Disalicylimide typically involves reactions utilizing precursors such as salicylic acid and salicylamide. One documented method involves reacting salicylic acid with thionyl chloride, followed by a reaction with salicylamide in the presence of a base like DBU (1,8-diazabicyclo[5.4.0]undec-7-ene), and subsequent acid treatment. This multi-step process requires precise control over reaction conditions, including temperature, solvents, and reaction times, to achieve optimal yield and purity. As a trusted supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to mastering these chemical synthesis pathways.

Disalicylimide is particularly recognized for its role as an impurity of Deferasirox, an orally active iron chelator. In pharmaceutical quality control, it is vital to have reliable reference standards to identify and quantify such impurities. This is where high-purity Disalicylimide, often procured as Disalicylimide powder, becomes indispensable. Analytical laboratories rely on these standards to validate their testing methods and ensure that final drug products meet stringent regulatory requirements. Purchasing Disalicylimide from a reputable manufacturer in China like NINGBO INNO PHARMCHEM CO.,LTD. ensures the integrity of these critical analyses.

The properties of Disalicylimide, such as its white solid appearance and specific melting point (around 203-204°C), are well-documented. Its solubility in various solvents like DMSO and methanol is also a key consideration for its use in analytical procedures. For researchers and manufacturers seeking to buy Disalicylimide powder, understanding these characteristics is important for handling and application. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive technical data and support for our products, including Disalicylimide, to facilitate its effective use in research and production.

In summary, Disalicylimide (CAS 1972-71-0) is a compound with multifaceted importance in the pharmaceutical sector. Its synthesis via intricate chemical synthesis pathways, its role as a critical Deferasirox impurity, and its availability as a high-purity standard highlight its value. NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to the pharmaceutical supply chain by offering quality Disalicylimide to researchers and manufacturers worldwide.