The Synthesis Pathway of Aripiprazole: Role of 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone
The development and production of effective pharmaceuticals rely heavily on the availability and precise handling of key chemical intermediates. Among these, 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone, identified by CAS number 129722-34-5, stands out as a critical component in the synthesis pathway of Aripiprazole, a widely prescribed antipsychotic medication. At NINGBO INNO PHARMCHEM CO.,LTD., we understand the intricate chemistry involved in bringing life-changing drugs to market, and this intermediate is a cornerstone of that process.
The synthesis of Aripiprazole is a multi-step chemical reaction, and 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone acts as a crucial building block. Its specific molecular structure, featuring a quinolinone core with a bromobutoxy side chain, is designed to react precisely with other precursors to form the final active pharmaceutical ingredient (API). The efficiency and purity of this intermediate directly impact the overall yield and quality of the Aripiprazole produced. Ensuring the highest purity of 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone is paramount, as even trace impurities can affect the efficacy or safety of the final drug product. This focus on purity aligns with our commitment to providing top-tier pharmaceutical intermediates for drug development.
Furthermore, understanding the potential formation of 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone as an impurity or degradation product within the Aripiprazole synthesis is vital for robust quality control. Analytical chemists at NINGBO INNO PHARMCHEM CO.,LTD. diligently develop and implement methods to monitor and quantify such impurities, ensuring that the final API meets stringent regulatory standards. This proactive approach to impurity profiling is a testament to our dedication to pharmaceutical excellence and patient safety. For companies seeking reliable suppliers for drug development, the availability of high-quality 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone is a significant factor in streamlining their research and production timelines, facilitating the journey from laboratory synthesis to patient care.
Perspectives & Insights
Data Seeker X
“The synthesis of Aripiprazole is a multi-step chemical reaction, and 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone acts as a crucial building block.”
Chem Reader AI
“Its specific molecular structure, featuring a quinolinone core with a bromobutoxy side chain, is designed to react precisely with other precursors to form the final active pharmaceutical ingredient (API).”
Agile Vision 2025
“The efficiency and purity of this intermediate directly impact the overall yield and quality of the Aripiprazole produced.”