The field of organic synthesis is continually enriched by compounds that offer a unique blend of reactivity and structural versatility. 4-(1H-Imidazol-1-yl)benzoic acid (CAS 17616-04-5) is one such molecule, prized by chemists for its dual functionality and its utility as a key intermediate. Understanding the detailed chemical properties of 4-(1H-Imidazol-1-yl)benzoic acid is crucial for unlocking its full potential in various synthetic pathways, particularly in the pharmaceutical and fine chemical industries.

This compound features an imidazole ring, a five-membered aromatic heterocycle known for its basicity, nucleophilicity, and ability to engage in hydrogen bonding and metal coordination. Attached to this is a benzoic acid group, providing an acidic carboxyl functional group. This combination makes 4-(1H-Imidazol-1-yl)benzoic acid an excellent candidate for a wide array of chemical transformations. For instance, the carboxyl group can readily participate in esterification, amidation, and decarboxylation reactions. The imidazole nitrogen atoms can be alkylated or acylated, and the aromatic rings can undergo electrophilic or nucleophilic substitutions under specific conditions.

The significance of 4-(1H-Imidazol-1-yl)benzoic acid as a pharmaceutical intermediate stems from the prevalence of imidazole and benzoic acid motifs in biologically active molecules. Researchers looking to synthesize novel drug candidates often seek to buy 4-(1H-Imidazol-1-yl)benzoic acid to incorporate these pharmacologically relevant structural elements. Its typical purity of 97% or higher ensures that it can be integrated into complex multi-step syntheses with a high degree of confidence, minimizing the risk of side products or reduced yields.

In fine chemical synthesis, the compound’s versatility is further leveraged. It can serve as a ligand in the formation of metal-organic frameworks (MOFs), which have applications in gas storage, catalysis, and separation technologies. Furthermore, its structure can be modified to create advanced materials for optoelectronics or specialized polymers. For laboratories and manufacturing facilities, securing a consistent supply of high-quality 4-(1H-Imidazol-1-yl)benzoic acid is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers and industries with this vital chemical building block, supporting advancements across diverse scientific disciplines. Whether you need to buy 4-(1H-Imidazol-1-yl)benzoic acid for research or production, our focus on quality and reliability ensures your synthetic goals are met.