The pharmaceutical industry relies on a sophisticated chain of chemical synthesis, where each intermediate plays a crucial role. Tert-Butyl 3-Oxo-1-Phenylpropylcarbamate, identified by CAS number 135865-78-0, stands out as a pivotal precursor in the synthesis of Maraviroc, an essential drug for HIV management. A thorough understanding of its chemical and physical properties is fundamental for researchers and manufacturers aiming to optimize drug production and ensure therapeutic efficacy.

Commonly referred to by its synonyms such as N-Boc-(3S)-3-phenyl-3-aminopropionaldehyde, this compound exhibits specific characteristics that make it suitable for its intended use. Its molecular formula is C14H19NO3, with a molecular weight of approximately 249.31 g/mol. The compound is typically presented as a white solid or foam, with specifications often detailing its assay (HPLC) to be 98.0% or higher. This high purity is a non-negotiable requirement for its application in pharmaceutical synthesis, ensuring that downstream reactions proceed smoothly and the final product meets stringent quality controls.

The physical properties, such as density and boiling point, provide further insights into its handling and stability. With a density of approximately 1.1 g/cm³ and a high boiling point (around 371.9 °C at 760 mmHg), it suggests a relatively stable compound under normal storage conditions. However, adherence to recommended storage guidelines, such as keeping it in a cool, ventilated place, is vital to maintain its integrity and reactivity.

The significance of CAS 135865-78-0 lies primarily in its role as a Maraviroc intermediate. Maraviroc, an entry inhibitor, targets the CCR5 co-receptor, preventing the human immunodeficiency virus (HIV) from entering host cells. The synthesis of this complex molecule involves the careful assembly of several chemical fragments, and Tert-Butyl 3-Oxo-1-Phenylpropylcarbamate provides a key chiral segment. Its precise stereochemistry is critical for the biological activity of Maraviroc, highlighting the importance of sourcing from reliable suppliers who guarantee enantiomeric purity.

When seeking to buy Tert-Butyl 3-Oxo-1-Phenylpropylcarbamate, it is essential to consider factors beyond just the chemical name and CAS number. Potential buyers should inquire about the supplier's quality control processes, their capacity to meet demand, and their compliance with relevant industry regulations. The availability of detailed technical documentation, such as Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS), is also a strong indicator of a reputable supplier.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering high-quality pharmaceutical intermediates, including Tert-Butyl 3-Oxo-1-Phenylpropylcarbamate, to support the global healthcare sector. Our focus on purity, reliability, and customer service ensures that our clients receive materials that meet their exact specifications, facilitating the successful production of essential medicines.

In essence, understanding the detailed properties of intermediates like CAS 135865-78-0 is fundamental to the advancement of pharmaceutical sciences. It is through the careful selection and utilization of these building blocks that groundbreaking treatments like Maraviroc can be brought to patients worldwide.