The chemical compound identified by CAS number 98556-31-1, known as 4-Chloro-6-iodoquinazoline, is a critical molecule within the fine chemical and pharmaceutical industries. Its primary significance lies in its role as a key intermediate in the synthesis of Lapatinib, a powerful anti-cancer drug that targets specific receptor tyrosine kinases involved in tumor growth. NINGBO INNO PHARMCHEM CO.,LTD. recognizes the importance of providing high-quality intermediates like 4-Chloro-6-iodoquinazoline to support the development and production of essential medicines.

Delving into the chemical aspects, 4-Chloro-6-iodoquinazoline is a heterocyclic aromatic organic compound. Its structure, featuring a quinazoline core substituted with a chlorine atom at the 4-position and an iodine atom at the 6-position, provides specific reactive sites that are essential for subsequent chemical transformations. These properties make it an ideal building block for constructing more complex pharmaceutical molecules. The compound typically appears as a solid, often described as light brown to dark grey, with a melting point in the range of 175.0 to 179.0 °C, indicating its stability under standard conditions.

The applications of 4-Chloro-6-iodoquinazoline are primarily concentrated in the pharmaceutical sector, specifically in the Lapatinib production process. Lapatinib, marketed under brand names like Tykerb, is a tyrosine kinase inhibitor used to treat HER2-positive breast cancer. The precise chemical structure of 4-Chloro-6-iodoquinazoline enables chemists to execute the necessary reaction steps to assemble the Lapatinib molecule efficiently and with high purity. This makes it an indispensable component in the pharmaceutical synthesis of this critical oncology drug.

The meticulous chemical synthesis involved in creating Lapatinib relies heavily on the purity and reactivity of its intermediates. For manufacturers, sourcing pharmaceutical intermediates like 4-Chloro-6-iodoquinazoline from reputable suppliers is crucial to ensure the final drug's safety and efficacy. Companies like NINGBO INNO PHARMCHEM CO.,LTD. play a vital role by ensuring a consistent supply of this key compound, adhering to strict quality control measures throughout their production processes.

Furthermore, the broader field of chemical research also benefits from the availability of 4-Chloro-6-iodoquinazoline. Researchers may utilize it to explore novel reaction pathways, develop new synthetic methodologies for related compounds, or investigate the medicinal properties of other quinazoline derivatives. As a versatile molecule, it contributes to the ongoing advancement of organic chemistry and its applications in medicine.

The importance of CAS 98556-31-1 in the pharmaceutical supply chain cannot be overstated. It represents a critical link in the chain that brings advanced therapies to patients. By understanding the specific properties and applications of this intermediate, pharmaceutical professionals can better plan their manufacturing processes and ensure the timely availability of essential treatments. The consistent demand for advanced chemical intermediates for oncology is a testament to the ongoing innovation in cancer treatment, with compounds like 4-Chloro-6-iodoquinazoline being at the forefront of these developments.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality 4-Chloro-6-iodoquinazoline, supporting the global pharmaceutical industry's efforts to develop and produce vital medicines. Our focus on purity and reliable supply chains ensures that our partners can confidently integrate this intermediate into their critical synthesis processes.