Understanding the Chemical Properties and Applications of (R)-3-Aminopiperidine Dihydrochloride
(R)-3-Aminopiperidine Dihydrochloride, with its CAS number 334618-23-4, is a chemical compound of considerable interest within the scientific community, particularly for its utility as a building block in complex organic synthesis and pharmaceutical research. Its structure, featuring a piperidine ring with an amino group at the chiral center, makes it a valuable intermediate for creating molecules with specific biological activities. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing this high-quality compound to researchers and manufacturers globally.
From a chemical perspective, (R)-3-Aminopiperidine Dihydrochloride is typically presented as a white powder. Its physical state and appearance are consistent across various supplier data, indicating a stable compound under appropriate storage conditions. Importantly, it exhibits good solubility in water, a property that significantly aids its integration into various reaction schemes and formulations. This solubility profile simplifies handling and processing in laboratory and industrial settings alike.
The compound's molecular formula is C5H12N2·2HCl, with a molecular weight of approximately 173.08 g/mol. This precise chemical composition is crucial for stoichiometric calculations in synthesis. Its melting point is reported to be in the range of 190-195°C, suggesting a relatively stable solid structure. Safety data indicates it is harmful if swallowed and can cause skin irritation, serious eye damage, and respiratory irritation, necessitating appropriate handling precautions and the use of personal protective equipment during its use. NINGBO INNO PHARMCHEM CO.,LTD. always provides comprehensive safety data sheets to ensure the safe handling and use of this chemical.
The primary application driving the demand for (R)-3-Aminopiperidine Dihydrochloride is its role as a pharmaceutical intermediate. It is instrumental in the synthesis of several important drugs. One of the most prominent uses is in the production of Alogliptin, a medication used to treat type 2 diabetes by inhibiting the enzyme dipeptidyl peptidase IV (DPP-IV). The specific chirality of the (R)-isomer is critical for the efficacy of Alogliptin, making the purity and stereochemical integrity of this intermediate paramount. Researchers also find utility in its application for studies concerning neurotransmitter systems, contributing to a deeper understanding of neurological functions and the development of treatments for related disorders.
Furthermore, the compound serves as a versatile component in broader organic synthesis endeavors. Chemists utilize it as a chiral building block to construct complex molecular architectures, which can then be explored for various applications, including the development of new materials or as intermediates for other fine chemicals. The ability to buy this intermediate from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that research and manufacturing projects can proceed without interruption, maintaining consistent product quality.
Perspectives & Insights
Chem Catalyst Pro
“This precise chemical composition is crucial for stoichiometric calculations in synthesis.”
Agile Thinker 7
“Its melting point is reported to be in the range of 190-195°C, suggesting a relatively stable solid structure.”
Logic Spark 24
“Safety data indicates it is harmful if swallowed and can cause skin irritation, serious eye damage, and respiratory irritation, necessitating appropriate handling precautions and the use of personal protective equipment during its use.”