For chemists and researchers engaged in the synthesis of complex organic molecules, a thorough understanding of intermediate compounds is crucial. Methyl 6-(bromomethyl)nicotinate (CAS 131803-48-0) is one such compound, prized for its utility in various chemical reactions. NINGBO INNO PHARMCHEM CO.,LTD. offers insights into its fundamental chemical properties and synthesis, ensuring users can effectively incorporate it into their research and development efforts.

Methyl 6-(bromomethyl)nicotinate is a derivative of nicotinic acid, featuring a pyridine ring substituted with a bromomethyl group at the 6-position and a methyl ester at the 3-position. This structure imparts specific chemical characteristics. Its physical form is typically an off-white solid, with a defined melting point and solubility profile that are critical for experimental planning. The compound's key physical properties, such as its boiling point (around 284.9±30.0℃) and density (approximately 1.533±0.06 g/cm³), are important considerations for handling and reaction design. Safety data sheets (SDS) often detail its hazard classifications, such as being an irritant, which guides appropriate laboratory practices.

The synthesis of methyl 6-(bromomethyl)nicotinate generally involves bromination reactions, often starting from a precursor like methyl 6-methylnicotinate. Using reagents such as N-bromosuccinimide in the presence of radical initiators like benzoyl peroxide, chemists can selectively introduce the bromine atom onto the methyl group. The successful methyl 6-(bromomethyl)nicotinate synthesis requires careful control of reaction conditions, including temperature, solvent, and reactant ratios, to maximize yield and purity. The ability to reliably buy methyl 6-(bromomethyl)nicotinate from reputable sources like NINGBO INNO PHARMCHEM CO.,LTD. simplifies the procurement process for researchers.

Understanding the compound's handling and storage requirements is also vital. Typically, it is stored under an inert atmosphere at refrigerated temperatures (2-8°C) to maintain its stability and prevent degradation. Proper safety precautions, including the use of personal protective equipment (PPE) and working in well-ventilated areas, are essential due to its irritant properties. The competitive methyl 6-(bromomethyl)nicotinate price offered by various suppliers ensures accessibility for a broad range of research projects, from small-scale laboratory experiments to larger pilot-scale syntheses.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting chemical research by providing high-quality intermediates. Their expertise in chemical synthesis and reliable supply chain management ensures that researchers have access to essential compounds like methyl 6-(bromomethyl)nicotinate, facilitating innovation in organic chemistry and related scientific fields.