For professionals involved in the procurement of pharmaceutical intermediates, a thorough understanding of product specifications is non-negotiable. D-Serine, a critical building block in pharmaceutical synthesis, particularly for drugs like Lacosamide, requires careful attention to its quality parameters. NINGBO INNO PHARMCHEM CO.,LTD. aims to educate buyers on the essential specifications that define high-quality D-Serine, ensuring successful integration into their manufacturing processes.

The identity of D-Serine is confirmed by its CAS number: 312-84-5. Visually, it appears as a white crystalline powder. However, the true measure of its suitability for pharmaceutical use lies in its detailed chemical and physical properties. The assay, a measure of the compound's purity, is typically expected to be ≥98.0%. This ensures that the majority of the material consists of the desired D-Serine molecule, minimizing the presence of inactive or potentially interfering substances. When considering the Lacosamide synthesis from D-serine, this purity is fundamental for achieving high yields.

Perhaps the most critical specification for D-Serine in pharmaceutical applications is its chiral purity. As a chiral molecule, it exists as specific enantiomers, and for Lacosamide synthesis, the D-enantiomer is required. Therefore, suppliers will specify a chiral purity, often ≥99.5%. This level of stereochemical control is vital to avoid the production of racemic mixtures or unwanted enantiomers of the final API. Buyers looking to buy D-serine for lacosamide synthesis must verify these chiral purity figures rigorously. Other important specifications include loss on drying (≤0.25%), indicating low moisture content, and residue on ignition (≤0.10%), reflecting minimal inorganic impurities. Limits on heavy metals (≤10ppm), chloride (≤0.02%), and arsenic (≤10ppm) are also standard requirements in pharmaceutical-grade materials.

Choosing a reputable CAS 312-84-5 D-serine supplier is key to obtaining material that consistently meets these stringent D-serine chiral purity specifications. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing D-Serine that not only meets but often exceeds these critical benchmarks, thereby supporting efficient and compliant Lacosamide production and other complex pharmaceutical syntheses.