The field of peptide chemistry is continuously evolving, driven by the need for increasingly sophisticated molecules for therapeutic and diagnostic purposes. Central to this progress is the availability of specialized amino acid derivatives, such as Fmoc-3-(2-Naphthyl)-D-Alanine. As a leading provider of fine chemicals in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-quality compounds that empower researchers in this domain.

Fmoc-3-(2-Naphthyl)-D-Alanine is a non-proteinogenic amino acid derivative characterized by the Fmoc protecting group, which is crucial for its application in solid-phase peptide synthesis (SPPS). The Fmoc group allows for facile removal under mild basic conditions, making it compatible with various sensitive peptide sequences. The D-alanine backbone and the 2-naphthyl side chain contribute unique steric and hydrophobic properties, which can significantly influence the structure, stability, and receptor-binding characteristics of synthesized peptides. Researchers often analyze the buy price and purity of such specialized amino acids to ensure optimal experimental outcomes.

The synthesis of Fmoc-3-(2-Naphthyl)-D-Alanine typically involves the reaction of 3-(2-Naphthyl)-D-alanine with Fmoc-Cl or Fmoc-OSu. The resulting compound, identified by its CAS number 138774-94-4, is a white to off-white crystalline powder. Its importance in peptide chemistry stems from its utility in constructing peptides with enhanced properties. For example, it serves as a key intermediate in the synthesis of specific tetrapeptides that have been investigated for their potential to inhibit the BRCA1 protein, indicating its relevance in cancer research.

Beyond its direct role in forming peptide bonds, Fmoc-3-(2-Naphthyl)-D-Alanine also finds applications in more specialized areas of chemical research. Its fluorescent properties, due to the naphthyl group, make it useful in supramolecular chemistry and as a probe in microscopy studies. The ability to form micelles and interact with various matrices, including DNA, further expands its potential use cases in advanced materials and biochemical assays.

NINGBO INNO PHARMCHEM CO.,LTD. is a reputable manufacturer and supplier in China, committed to providing researchers with precisely synthesized and highly pure Fmoc-3-(2-Naphthyl)-D-Alanine. We understand the critical nature of reliable peptide synthesis reagents and strive to maintain the highest quality standards. Our dedication to customer satisfaction ensures that researchers can confidently buy our products for their demanding projects, whether they are focused on fundamental research or the development of novel therapeutics.

In conclusion, Fmoc-3-(2-Naphthyl)-D-Alanine is a pivotal compound in modern peptide chemistry, offering researchers a versatile tool for synthesizing peptides with tailored properties. Its specific structure and protective group strategy facilitate advancements in drug discovery, chemical biology, and materials science. For reliable sourcing of this essential intermediate, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted manufacturer and supplier in China.