Folinic Acid Calcium Salt, more commonly known as Leucovorin Calcium, is a critical pharmaceutical compound with a significant impact on patient care, particularly in the fields of oncology and hematology. This biologically active form of folic acid is indispensable for reversing the toxic effects of dihydrofolate reductase inhibitors and augmenting the activity of certain antimetabolite chemotherapies. For healthcare providers and pharmaceutical manufacturers, understanding its applications and ensuring a reliable supply chain is paramount. NINGBO INNO PHARMCHEM CO.,LTD. offers high-quality Folinic Acid Calcium Salt, catering to the stringent demands of the global market.

One of the most critical uses of Folinic Acid Calcium Salt is its role as an antidote to methotrexate toxicity. Methotrexate, a widely used chemotherapy agent, can cause severe side effects by depleting the body's folate reserves. Folinic acid (Leucovorin) acts as a 'rescue' agent by providing cells with a reduced folate source, thereby mitigating the damage caused by methotrexate. This is especially important in high-dose methotrexate regimens used for treating various cancers. The prompt and correct administration of folinic acid calcium salt is crucial for patient survival and recovery following such treatments.

In the realm of cancer treatment, Folinic Acid Calcium Salt is also a key component in combination therapies. It is frequently administered alongside 5-fluorouracil (5-FU) for the treatment of advanced colorectal cancer. This combination, often referred to as 'Mayo Clinic regimen' or '5-FU/LV,' enhances the cytotoxic effect of 5-FU by stabilizing its binding to thymidylate synthase. This potentiation allows for more effective inhibition of DNA synthesis in cancer cells, leading to improved treatment outcomes. Patients seeking leucovorin calcium for cancer treatment rely on the consistent quality of this compound.

Beyond its oncological applications, Folinic Acid Calcium Salt is also prescribed for certain types of anemia. Specifically, it is used to treat megaloblastic anemias that are caused by folic acid deficiency. In these cases, it directly replenishes the body's folate levels, correcting the deficiency and restoring normal hematopoiesis.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing pharmaceutical-grade Folinic Acid Calcium Salt that adheres to international quality benchmarks, including USP, BP, EP, and FCC standards, with a minimum assay of 99.5%. Our commitment to quality ensures that our clients receive a reliable product for their formulation needs. We also facilitate easy access through our online platform, where inquiries regarding leucovorin calcium price can be made, and orders can be placed with confidence. For those looking to buy leucovorin calcium, our company provides a dependable and competitive sourcing option.

In summary, Folinic Acid Calcium Salt is a multifaceted pharmaceutical ingredient vital for patient safety and treatment efficacy in several critical medical conditions. Its role as an antidote and a chemotherapeutic enhancer underscores its importance in modern medicine. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the healthcare sector by supplying high-purity Folinic Acid Calcium Salt, ensuring that patients and medical professionals benefit from its life-saving properties.