The world of hematology diagnostics relies on a suite of specialized reagents, each with a distinct and critical role. For laboratory professionals, understanding these categories – primarily diluents, lysing reagents (lysates), and cleaners – is fundamental to operating analyzers efficiently and accurately. NINGBO INNO PHARMCHEM CO.,LTD. offers a comprehensive range of these essential products, including our EZ Cleaner 100ml, and is pleased to clarify their functions.

Diluents: These are the most frequently used reagents in hematology. Their primary purpose is to prepare the blood sample for analysis by diluting it to a specific concentration. This dilution process is essential for several reasons. Firstly, it reduces the viscosity of the blood, making it easier for the analyzer to count individual cells. Secondly, it ensures that cells are spaced appropriately within the fluid stream as they pass through the detection system, preventing them from clustering and leading to inaccurate counts. Diluents are also isotonic, meaning they have the same salt concentration as the blood cells, preventing them from swelling or shrinking and thus preserving their integrity during the analysis. High-quality diluents are crucial for all hematology analyzers, whether they are 3-part or 5-part differential models.

Lysing Reagents (Lysates): Lysates play a key role in differentiating and counting different types of blood cells. Their main function is to lyse, or break open, the red blood cells (erythrocytes). This is necessary because red blood cells are by far the most numerous cells in the blood, and their presence can interfere with the accurate counting and sizing of other cells, particularly white blood cells (leukocytes) and platelets. Lysing reagents are formulated to selectively break down the membrane of red blood cells while leaving the white blood cells intact, allowing for their distinct analysis. Different types of lyses are used, depending on whether the analyzer is a 3-part or 5-part differential system, with the latter requiring reagents that can also differentiate specific white blood cell populations.

Cleaners: As discussed previously, keeping the analyzer's internal pathways free of residue is critical. Cleaners are specifically designed to dissolve and flush away the various biological materials and other contaminants that can accumulate over time. These reagents are vital for preventing carryover between samples, maintaining the integrity of the optical or electrical detection systems, and ensuring overall instrument health. A robust cleaner, like our EZ Cleaner, is indispensable for routine maintenance. For users of brands like Mindray, finding compatible probe cleaner for Mindray analyzers is a key part of their maintenance strategy.

At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the performance of your hematology analyzer is directly linked to the quality and proper use of these reagents. By providing high-quality, ISO-certified diluents, lyses, and cleaners, we aim to support laboratories in achieving accurate, reliable, and efficient diagnostic testing. Whether you are looking to buy Mindray hematology reagents or seeking general laboratory supplies, ensuring the correct type of reagent is used for each function is a fundamental step towards diagnostic excellence.