Methyl 2-methyl-3-nitrobenzoate, with the CAS number 59382-59-1, is a compound of significant interest in the field of chemical synthesis. Its molecular formula, C9H9NO4, and molecular weight of 195.17 hint at its utility as a fine chemical intermediate. Typically appearing as a white powder, this compound is characterized by a melting point range of 62-65°C, making it a solid under standard conditions. Its solubility in methanol further defines its handling and reaction properties, crucial for effective utilization in synthetic processes.

The primary recognized application for Methyl 2-methyl-3-nitrobenzoate is its role as an essential pharmaceutical intermediate, particularly in the synthesis of Lenalidomide. This connection highlights its importance in the production of active pharmaceutical ingredients (APIs) and its contribution to the healthcare sector. As an organic synthesis building block, it enables chemists to efficiently construct more complex molecules, often serving as a critical step in multi-stage synthetic routes.

The synthesis of Methyl 2-methyl-3-nitrobenzoate itself involves established chemical methodologies, often starting from related benzoic acid derivatives. For instance, esterification of 2-methyl-3-nitrobenzoic acid with methanol, typically in the presence of an acid catalyst like thionyl chloride, yields the desired product. This process, when optimized, can provide high yields and purity, which are essential for its use as a pharmaceutical intermediate.

Beyond its direct use in drug manufacturing, Methyl 2-methyl-3-nitrobenzoate is also valuable in research laboratories. Its structure provides a platform for exploring various chemical reactions, leading to the synthesis of diverse organic compounds, including indole derivatives and other heterocyclic systems. This makes it a versatile component for chemists involved in discovery research, where access to reliable organic synthesis building blocks is key to innovation.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying high-quality Methyl 2-methyl-3-nitrobenzoate to meet the demands of researchers and manufacturers. Understanding the specific requirements of using this pharmaceutical intermediate with CAS 59382-59-1, we ensure our product meets rigorous purity standards. Whether for its role as an anticancer drug precursor or as a general building block in fine chemical synthesis, Methyl 2-methyl-3-nitrobenzoate remains a compound of considerable industrial and scientific importance.