NINGBO INNO PHARMCHEM CO.,LTD. provides a range of Microcrystalline Cellulose (MCC) grades, each with unique characteristics tailored for specific pharmaceutical applications. Understanding these differences is key for formulators to achieve optimal tablet and capsule performance. This guide aims to clarify the properties and selection criteria for various MCC grades.

Microcrystalline Cellulose, often abbreviated as MCC, is derived from highly purified cellulose. The numbering system, such as '101', '102', '200', '301', and '302', typically denotes variations in particle size, bulk density, and moisture content. These seemingly subtle differences can have a significant impact on the functional properties of the final dosage form.

MCC 101: Generally characterized by finer particles, it is often preferred for applications requiring excellent direct compression and wet granulation capabilities. Its fine particle size contributes to good flow and compressibility.

MCC 102: This is one of the most widely used grades. It offers a balance of particle size and bulk density, making it a versatile choice for both wet and dry granulation and direct compression. Its high compressibility and good binding properties are particularly valuable.

MCC 200: Featuring larger particles, MCC 200 typically exhibits superior flowing properties. This grade is beneficial when dealing with APIs that have poor flow characteristics or when improved powder movement is desired in the manufacturing process.

MCC 301 and 302: These grades often represent variations with lower moisture content compared to their counterparts like 101 and 102. Lower moisture content can be advantageous for moisture-sensitive APIs, helping to maintain their stability within the formulation.

When deciding which MCC grade to buy, formulators must consider several factors: the API's properties (e.g., compressibility, flow, moisture sensitivity), the desired dosage form (tablet or capsule), and the manufacturing process (direct compression, wet granulation, etc.). The microcrystalline cellulose pharmaceutical excipient selection is critical for overall product success.

The microcrystalline cellulose powder price can also vary between grades, reflecting differences in production complexity and performance characteristics. NINGBO INNO PHARMCHEM CO.,LTD. ensures that clients receive not only high-quality MCC but also the technical support needed to select the most appropriate grade for their specific formulation needs. Understanding the MCC binder properties and MCC disintegrant function in the context of different grades is essential for optimizing tablet performance.