At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the selection of the right Microcrystalline Cellulose (MCC) grade is critical for successful tablet formulation. MCC is renowned for its exceptional compressibility, binding, and disintegration properties, making it a cornerstone excipient in the pharmaceutical industry. However, the availability of various grades means that choosing the most suitable one is paramount to achieving desired product characteristics.

MCC's versatility allows it to be used in different manufacturing processes, including direct compression and wet granulation. For direct compression, grades like MCC 101 and MCC 102 are widely favored. MCC 101, with its smaller particle size, offers excellent compressibility and is suitable for a broad range of applications. MCC 102, characterized by a slightly larger particle size, provides improved flowability, which is beneficial for high-speed tableting operations. When you buy microcrystalline cellulose, understanding these subtle differences can optimize your process.

In wet granulation, MCC's hydrophilic nature and water-absorbing capabilities are advantageous. It aids in the even distribution of granulating fluid, leading to uniform granules and consistent drying. Grades that offer a good balance of particle size and moisture content are preferred. The role of MCC here is not just as a binder but also in managing the moisture within the granulation mass, preventing issues like overwetting and ensuring better granule quality.

For specific applications, such as moisture-sensitive drugs, specialized MCC grades with lower moisture content, like MCC 112 or MCC 113, are available. These grades help maintain the stability of the API throughout the manufacturing process. Additionally, MCC’s unique properties also make it suitable for other applications, including as a spheronizing aid in multiparticulate systems and as a texturizer in food and cosmetic products.

The consistent quality and predictable performance of pharmaceutical grade microcrystalline cellulose are what set it apart. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing MCC that meets global standards, ensuring batch-to-batch consistency for our clients. By understanding the nuances of different MCC grades and their specific MCC powder applications, manufacturers can enhance tabletability, improve manufacturing efficiency, and ultimately deliver superior pharmaceutical products.