Understanding Povidone K30: Properties, Synthesis, and Safety
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive information on the products we supply, including Povidone K30 (PVP K30). This widely used polymer, known chemically as polyvinylpyrrolidone, possesses a unique set of properties that have made it indispensable in various industries, particularly pharmaceuticals and cosmetics. Understanding its core characteristics, how it's made, and its safety is vital for effective utilization.
Povidone K30 is characterized by its water-soluble nature and its ability to dissolve in various organic solvents. It typically appears as a white to light yellow, hygroscopic, and amorphous powder. Its K-value, which indicates its molecular weight and viscosity, is crucial for determining its suitability for specific applications. For instance, the PVP K30 pharmaceutical excipient is selected for its excellent film-forming capabilities, strong adhesive properties, and chemical stability, all while being non-toxic and safe for human use in approved applications.
Historically, Povidone was first synthesized by Walter Reppe at BASF in 1939. Its initial application was as a blood plasma substitute. Since then, its use has expanded dramatically. The synthesis of Povidone K30 involves the polymerization of N-vinylpyrrolidone monomer. This process allows for the production of polymers with a wide range of molecular weights, offering formulators flexibility in achieving desired product characteristics. The consistent quality of PVP K30 pharmaceutical excipient from NINGBO INNO PHARMCHEM CO.,LTD. ensures reliable performance in every batch.
The safety profile of Povidone K30 is well-established. The U.S. Food and Drug Administration (FDA) has approved it for numerous uses, and it is generally recognized as safe (GRAS). It is listed in the FDA's Inactive Ingredient Database for oral, topical, and injectable formulations. While rare allergic reactions have been documented, they are often associated with specific routes of administration or co-exposure to other substances. NINGBO INNO PHARMCHEM CO.,LTD. adheres to strict quality control measures to ensure the purity and safety of our Povidone K30, making it a reliable dissolving assistant for injection and a host of other applications.
The versatility of Povidone K30 extends to its use as a binder in tablets, a dissolving assistant in injections, a solubility enhancer for poorly soluble drugs, and a bioavailability enhancer. Its hygroscopic nature aids in moisture retention where needed, while its film-forming capacity is beneficial in coatings and personal care products. As a PVP K30 pharmaceutical excipient, it contributes significantly to the efficacy and stability of numerous medicinal products. The reliability and safety of Povidone K30 make it a cornerstone ingredient for innovation in the pharmaceutical sector.
Perspectives & Insights
Quantum Pioneer 24
“is committed to providing comprehensive information on the products we supply, including Povidone K30 (PVP K30).”
Bio Explorer X
“This widely used polymer, known chemically as polyvinylpyrrolidone, possesses a unique set of properties that have made it indispensable in various industries, particularly pharmaceuticals and cosmetics.”
Nano Catalyst AI
“Understanding its core characteristics, how it's made, and its safety is vital for effective utilization.”