Understanding the Properties and Uses of 4-Chloro-2-fluorobenzoic Acid (CAS 446-30-0)
NINGBO INNO PHARMCHEM CO.,LTD. provides a detailed overview of 4-Chloro-2-fluorobenzoic acid (CAS 446-30-0), a compound of significant interest due to its versatile chemical nature and broad applicability. This article delves into its key physical and chemical properties, essential for researchers and industrial users alike. Understanding these characteristics is crucial for optimizing its use in various synthetic processes.
Key properties of 4-Chloro-2-fluorobenzoic acid include its appearance as an off-white to white powder, with a high purity typically exceeding 99.0% as determined by HPLC. It possesses a melting point in the range of 204-208°C and a boiling point of approximately 274.7°C. These parameters are vital for handling and processing the chemical safely and effectively. The compound's insolubility in water and specific solubility in organic solvents dictate its suitability for different reaction conditions. As a chemical synthesis intermediate, these physical attributes play a critical role in reaction design and purification stages.
Safety information is also paramount when working with any chemical. 4-Chloro-2-fluorobenzoic acid is classified as an irritant (Xi) and harmful if swallowed (Xn), with hazard statements including H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Standard precautionary statements such as P261 (Avoid breathing dust/fume/gas/mist/vapors/spray) and P280 (Wear protective gloves/protective clothing/eye protection/face protection) are recommended. NINGBO INNO PHARMCHEM CO.,LTD. ensures that all necessary safety data sheets (SDS) are available to our clients, promoting safe handling and usage practices.
The primary applications of 4-Chloro-2-fluorobenzoic acid as a chemical synthesis intermediate are well-established. It serves as a critical starting material for synthesizing pharmaceuticals like furosemide, a widely used diuretic. In agrochemical research, it's employed in the creation of novel herbicides. Furthermore, its potential utility in material science, such as in the preparation of liquid crystals, highlights its broad impact. Access to reliable chemical synthesis intermediates like this is fundamental for driving innovation across these vital industries.
Perspectives & Insights
Bio Analyst 88
“As a chemical synthesis intermediate, these physical attributes play a critical role in reaction design and purification stages.”
Nano Seeker Pro
“4-Chloro-2-fluorobenzoic acid is classified as an irritant (Xi) and harmful if swallowed (Xn), with hazard statements including H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).”
Data Reader 7
“Standard precautionary statements such as P261 (Avoid breathing dust/fume/gas/mist/vapors/spray) and P280 (Wear protective gloves/protective clothing/eye protection/face protection) are recommended.”