Pyridine-3-sulfonyl Chloride, identified by its CAS number 16133-25-8, is more than just a chemical compound; it is a critical enabler of advancements in modern medicine. As a key pharmaceutical intermediate, its properties and applications are of significant interest to researchers and manufacturers alike. NINGBO INNO PHARMCHEM CO.,LTD. highlights the importance of understanding this compound for effective drug development, especially its role in the synthesis of Vonoprazan Fumarate.

The chemical properties of CAS 16133-25-8 are defined by its reactive sulfonyl chloride group and the pyridine ring. This combination allows it to readily participate in nucleophilic substitution reactions, making it an ideal candidate for forming new chemical bonds during complex organic synthesis. While it is a colorless to light yellow liquid, it is also noted for its sensitivity to moisture, readily hydrolyzing to pyridine-3-sulfonic acid and hydrochloric acid. This reactivity necessitates careful handling and storage, typically under inert conditions, to maintain its integrity and ensure its effectiveness in downstream applications.

The primary uses of Pyridine-3-sulfonyl Chloride are firmly rooted in the pharmaceutical sector. Its most prominent application is as a precursor in the synthesis of Vonoprazan Fumarate. This drug, a potent acid blocker, is revolutionizing the treatment of acid-related gastrointestinal conditions. The precise incorporation of the pyridine-3-sulfonyl moiety is fundamental to the pharmacological activity of Vonoprazan Fumarate. Beyond this, the compound serves as a valuable building block in other areas of organic chemistry, contributing to the development of novel molecules with potential therapeutic benefits. The demand for such specialized medical intermediates reflects the continuous drive for innovation in drug discovery and manufacturing.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying Pyridine-3-sulfonyl Chloride that meets rigorous quality standards. Our focus on purity and consistency ensures that our clients can reliably integrate this intermediate into their manufacturing processes. The successful production of acid blockers and other pharmaceuticals depends on the quality of every component, from raw materials to intermediates. By understanding and expertly managing the pharmaceutical intermediate production of compounds like Pyridine-3-sulfonyl Chloride, we empower our partners to bring life-changing therapies to market more efficiently and effectively.