Understanding Quinolinic Acid: A Crucial Player in Tryptophan Metabolism and Neurodegenerative Research
Quinolinic acid, identified by its CAS number 89-00-9, is a compound of significant interest in both biological research and chemical synthesis. As a biologically active dicarboxylic acid, it plays a pivotal role in the complex metabolic pathways of tryptophan, specifically within the kynurenine pathway. This position makes it a critical intermediate, offering valuable insights into how the body processes this essential amino acid.
In the realm of neuroscience, Quinolinic Acid is particularly renowned for its implications in neurodegenerative disorders. Researchers extensively utilize it to study phenomena such as excitotoxicity and to model conditions like Alzheimer's disease and Parkinson's disease. Its function as an NMDA receptor agonist is key to understanding neuronal signaling and the potential damage caused by overstimulation of these receptors. This makes it an indispensable tool for developing potential neuroprotective drug candidates.
Beyond its neurological relevance, Quinolinic Acid finds application in various organic synthesis processes, serving as a foundational chemical building block. Its unique structure also lends itself to use in biochemical assays, where precise chemical reagents are paramount for accurate results. Understanding the nuances of Quinolinic Acid, including its synthesis and handling, is crucial for researchers and chemical manufacturers alike. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality Quinolinic Acid, ensuring purity and reliability for your critical applications. Whether you are investigating complex biochemical pathways or synthesizing novel organic compounds, our supply of Quinolinic Acid can support your scientific endeavors.
Perspectives & Insights
Chem Catalyst Pro
“Researchers extensively utilize it to study phenomena such as excitotoxicity and to model conditions like Alzheimer's disease and Parkinson's disease.”
Agile Thinker 7
“Its function as an NMDA receptor agonist is key to understanding neuronal signaling and the potential damage caused by overstimulation of these receptors.”
Logic Spark 24
“This makes it an indispensable tool for developing potential neuroprotective drug candidates.”