In the relentless pursuit of more effective cancer treatments, the pharmaceutical industry constantly seeks novel compounds and intermediates that can serve as building blocks for groundbreaking therapies. Among these, the Pyrido[2,3-d]pyrimidin-7(8H)-one scaffold has emerged as a significant structural motif. Specifically, the compound identified by CAS number 571190-30-2, known chemically as 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-Pyrido[2,3-d]pyrimidin-7(8H)-one, plays a pivotal role as a pharmaceutical intermediate.

This particular derivative is intrinsically linked to the development of targeted therapies, most notably Palbociclib. Palbociclib is a potent and selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), which are critical regulators of the cell cycle. By inhibiting these kinases, Palbociclib effectively halts the progression of cancer cells, making it a vital component in the treatment of hormone receptor-positive, HER2-negative advanced or metastatic breast cancer. The precise synthesis of such complex molecules relies heavily on high-quality intermediates like the Pyrido[2,3-d]pyrimidin-7(8H)-one derivative we offer.

Our commitment at NINGBO INNO PHARMCHEM CO.,LTD. is to provide researchers and pharmaceutical manufacturers with precisely this caliber of intermediate. With a guaranteed purity of ≥99%, our white powder form of this compound ensures that your synthesis processes yield the highest quality end products. Understanding the critical nature of these components for drug discovery, we focus on ensuring consistency and reliability in every batch we supply. The demand for such intermediates is driven by ongoing research into new applications and improved efficacy of CDK inhibitors, making a dependable supplier paramount for accelerating the drug development pipeline.

Researchers often search for specific terms when looking for these essential components. For instance, they might look for 'Pyrido[2,3-d]pyrimidin-7(8H)-one derivative pharmaceutical intermediate' or 'CAS 571190-30-2 Palbociclib intermediate'. The ability to source these chemicals reliably and efficiently directly impacts the pace of scientific advancement. The applications of this Pyrido[2,3-d]pyrimidin-7(8H)-one derivative extend to its use as a reference standard in analytical chemistry, ensuring the accuracy and validity of testing protocols for related pharmaceutical compounds. This comprehensive utility underscores its importance in the pharmaceutical landscape.

As the field of oncology continues to evolve, the demand for specialized intermediates that enable the creation of more targeted and less toxic therapies will only grow. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting this progress by providing essential chemical components that empower scientific innovation. Our aim is to facilitate breakthroughs in cancer therapy by ensuring access to the foundational materials required for their development and production.