In the highly regulated pharmaceutical sector, precise specifications for chemical intermediates are non-negotiable. Tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate (CAS: 1426129-50-1), a vital intermediate for Sacubitril synthesis, is no exception. Understanding these specifications ensures that manufacturers procure material that meets the stringent requirements for drug production. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive product data to support our clients.

Key specifications for tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate typically include its Chemical Name: N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester. The CAS Number, 1426129-50-1, serves as a unique identifier in chemical databases and regulatory filings. Its Molecular Formula, C20H25NO3, and Molecular Weight, 327.41700 g/mol, are fundamental identifiers of the compound's composition.

The physical appearance is consistently described as a White or off-white powder, a visual cue that, alongside other analytical data, indicates product quality. Purity is a critical metric, with standards often set at >99%. This is further detailed by limits on single impurities (typically ≤ 0.5% max) and total impurities (≤ 2.0% max), ensuring a clean reaction profile when used in downstream synthesis.

For chiral compounds like this intermediate, chiral purity is also specified, often with a limit for chiral impurities (e.g., ≤ 0.5% max). This is critical as the stereochemistry of the intermediate directly impacts the efficacy of the final API. The melting point, usually within the range of 114-116 °C, provides another indicator of purity and identity. Storage conditions are also vital for maintaining product integrity, typically recommending storage in a well-closed container at low temperatures, protected from moisture, heat, and light.

NINGBO INNO PHARMCHEM CO.,LTD. ensures that each batch of tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate is accompanied by detailed specifications and analytical data. We understand that precise adherence to these standards is fundamental to successful pharmaceutical manufacturing and research, supporting the creation of safe and effective treatments such as Sacubitril.