The world of organic chemistry is rich with versatile compounds that serve as the foundational elements for numerous industrial and pharmaceutical applications. Among these, 5-Bromo-2,4-dichloropyrimidine (CAS No. 36082-50-5) stands out as a particularly important organic intermediate, recognized for its crucial role in the synthesis of complex molecules. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying this high-quality chemical, understanding its intricate synthesis and diverse applications.

The synthesis of 5-Bromo-2,4-dichloropyrimidine typically involves the chlorination of 5-bromouracil using reagents like phosphorus pentachloride. This process, while requiring careful control of reaction conditions, yields a compound with the molecular formula C4HBrCl2N2. The resulting product is usually a colorless to light yellow liquid, with exceptional purity standards often exceeding 99.0% when produced by reputable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. The precise arrangement of halogens on the pyrimidine ring grants it specific reactivity, making it a valuable building block in multi-step organic synthesis.

The primary application driving demand for 5-Bromo-2,4-dichloropyrimidine is its use as a key intermediate in the pharmaceutical industry. It is indispensable in the synthesis of Palbociclib and Ribociclib, two significant drugs used in the treatment of specific types of cancer. These drugs function as CDK4/6 inhibitors, offering targeted therapies that have shown remarkable efficacy in clinical trials and patient treatments. The reliable purchase of this intermediate ensures that pharmaceutical companies can maintain consistent production of these vital medications.

Beyond its critical role in oncology drug development, 5-Bromo-2,4-dichloropyrimidine also finds utility in other areas of chemical research and synthesis. Its halogenated pyrimidine structure allows for various functionalization reactions, including nucleophilic substitutions and palladium-catalyzed cross-coupling reactions. This versatility makes it an attractive starting material for researchers developing novel heterocyclic compounds, materials science innovations, and other fine chemicals. NINGBO INNO PHARMCHEM CO.,LTD. supports these diverse research endeavors by providing access to this indispensable chemical building block.

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to facilitating scientific and industrial progress through the provision of high-quality chemical intermediates. Our focus on stringent quality control and efficient supply chain management ensures that clients receive reliable access to 5-Bromo-2,4-dichloropyrimidine for their most demanding projects. We understand the intricate requirements of the chemical synthesis field and strive to be a trusted partner for all your intermediate needs.